Determination of the design space of chiral HPLC separations on chirobiotic T stationary phase / Nadine Medhat George Benyamin ; Supervised Rasha Sayed Hanafi , Lamia Ahmed Shihata , Hassan Y. Aboulenein
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قاعة الثقاقات الاجنبية - الدور الثالث | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.34.M.Sc.2017.Na.D (Browse shelf(Opens below)) | Not for loan | 01010110075335000 |
Thesis (M.Sc.) - German University - Faculty of Postgraduate Studies and Scientific Research - Department of Pharmaceutical Chemistry
The integration of QbD approach into development of chiral HPLC method for the determination of the desgin space of separation of chiral durgs is a mandatory request by the food and drug Administration and the International conference on harmonzation guidelines presently . The current study aims to determine the design space of the enantiomeric separation of three beta-adrenergic blockers ; atenolol , metoprolol and pindolol on Chirobiotic T column in polar ionic mode with the aid MINITAB® statistical software
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