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Femtosecond laser capsulotomy versus conventional capsulorhexis : A clinical and scanning electron microscopic study / Rana Mohammed Ali Harhara ; Supervised Ali Mohamed Taha , Hesham Fathallah Elsheikh , Yasmine Mohamed Elsayed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Rana Mohammed Ali Harhara , 2017Description: 109 P. : charts , facsimiles ; 25cmOther title:
  • قطع المحفظة الأمامية بواسطة الفيمتوليزر مقابل الطريقة التقليدية : دراسة اكلينيكية و بواسطة مجهر المسح الالكتروني [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Opthalmology Summary: Purpose: To analyze and compare the structure and regularity of capsulotomy cutting edges, and to assess the accuracy of the reproducibility of the centration and size of capsulotomy in both groups. Methods: Twenty anterior capsulotomies were obtained using FS laser cataract platform (Catalys, {u1D45B} = 20) group A .In addition, twenty manual CCC ({u1D45B} = 20) group B, were obtained using a rhexis forceps. The specimens were imaged by eSEM (Quanta FEG 250, Czech Republic), and were processed and analyzed using Image-Java software (version 1.5). Irregularity of the capsule edges were analyzed morphologically and quantified using 8 parameters; the arithmetic mean deviation of the surface (Sa),the root-mean-square deviation of the surface (Sq), the skewness of the topography height distribution (Ssk), the kurtosis of the topography height distribution (Sku), contrast, angular second moment, coefficient of variation (CoV), and the gray-level co-occurrence matrix measurements (Homogeneity). Centration and size of the capsules were also analyzed. Effective phacoemulsification power and time were evaluated and compared between both groups as secondary outcomes. Results: By SEM, morphologically the femtosecond laser{u2013}assisted capsulotomy edge surfaces showed marked irregularity compared with the smooth edge of the CCC. The edges of manually torn capsules were shown, by comparison of Sa and Sq values, to be smoother ({u1D443} = 0.01) than the FS laser capsulotomy edges. The Ssk values were lower in group A compared to group B (1.28 ± 0.17 vs.1.35 ± 0.17, P= 0.08).Similarly the Sku were also lower in group A than group B (2.14 ± 1.12 vs. 2.55 ± 1.11, P = 0.08). The angular second moment (P =0.01) and contrast (P =0.04) measures for both lasers differed significantly from those obtained for CCC .Although the laser capsulotomy edges were rougher ( 109.31 ± 2.40) than the manual capsulorhexes (110.93 ± 3.92) , the mean CoV values from the regression analysis was not statistically significant for bothhorizontal meridianeducing effective phacoemulsification time and power during lens fragmentation
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.24.Ph.D.2017.Ra.F (Browse shelf(Opens below)) Not for loan 01010110075601000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.24.Ph.D.2017.Ra.F (Browse shelf(Opens below)) 75601.CD Not for loan 01020110075601000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Opthalmology

Purpose: To analyze and compare the structure and regularity of capsulotomy cutting edges, and to assess the accuracy of the reproducibility of the centration and size of capsulotomy in both groups. Methods: Twenty anterior capsulotomies were obtained using FS laser cataract platform (Catalys, {u1D45B} = 20) group A .In addition, twenty manual CCC ({u1D45B} = 20) group B, were obtained using a rhexis forceps. The specimens were imaged by eSEM (Quanta FEG 250, Czech Republic), and were processed and analyzed using Image-Java software (version 1.5). Irregularity of the capsule edges were analyzed morphologically and quantified using 8 parameters; the arithmetic mean deviation of the surface (Sa),the root-mean-square deviation of the surface (Sq), the skewness of the topography height distribution (Ssk), the kurtosis of the topography height distribution (Sku), contrast, angular second moment, coefficient of variation (CoV), and the gray-level co-occurrence matrix measurements (Homogeneity). Centration and size of the capsules were also analyzed. Effective phacoemulsification power and time were evaluated and compared between both groups as secondary outcomes. Results: By SEM, morphologically the femtosecond laser{u2013}assisted capsulotomy edge surfaces showed marked irregularity compared with the smooth edge of the CCC. The edges of manually torn capsules were shown, by comparison of Sa and Sq values, to be smoother ({u1D443} = 0.01) than the FS laser capsulotomy edges. The Ssk values were lower in group A compared to group B (1.28 ± 0.17 vs.1.35 ± 0.17, P= 0.08).Similarly the Sku were also lower in group A than group B (2.14 ± 1.12 vs. 2.55 ± 1.11, P = 0.08). The angular second moment (P =0.01) and contrast (P =0.04) measures for both lasers differed significantly from those obtained for CCC .Although the laser capsulotomy edges were rougher ( 109.31 ± 2.40) than the manual capsulorhexes (110.93 ± 3.92) , the mean CoV values from the regression analysis was not statistically significant for bothhorizontal meridianeducing effective phacoemulsification time and power during lens fragmentation

Issued also as CD

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