header
Local cover image
Local cover image
Image from OpenLibrary

Molecular and protein levels assessment of oncostatin-m in oral squamous cell carcinoma : In vitro study / Noha Shaban Aboelyazeed ; Supervised Louloua Mohamed Fathi , Amal Hassan Abdelrahman , Dina Sabry Abdelfattah

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Noha Shaban Aboelyazeed , 2017Description: 102 P. : charts , facsimiles ; 25cmOther title:
  • التقييم الجزيئي والبروتيني للانكوستاتين-م للسرطانات الفموية الحرشفية : دراسة خارجية [Added title page title]
Subject(s): Online resources: Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University -Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Pathology Summary: Background: Growth of oral squamous cell carcinoma is generally associated with an inflammatory component. It is hypothesized that tumor cellsevade the growth inhibitory effects of cytokines present in the tumor microenvironment. Oncostatin-M (OSM) is an inflammatory cytokine produced by macrophages and T lymphocytes as well as tumor cells, it inhibits the proliferation and induces differentiation of a number of types of tumors. This study aimed to study OSM expression on both gene and protein levels. Methods:in vitro study done on thirty (OSCC) cases obtained from paraffin blocks and ten normal epithelial tissues used as control. For each case immunohistochemical examination of OSM protein intissues as well as quantitative real time polymerase chain reaction(RT-PCR) were done for determination of expression of both OSM gene and its specific receptor, finally results were statistically analyzed using ANOVA test
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.09.14.Ph.D.2017.No.M (Browse shelf(Opens below)) Not for loan 01010110075638000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.09.14.Ph.D.2017.No.M (Browse shelf(Opens below)) 75638.CD Not for loan 01020110075638000

Thesis (Ph.D.) - Cairo University -Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Pathology

Background: Growth of oral squamous cell carcinoma is generally associated with an inflammatory component. It is hypothesized that tumor cellsevade the growth inhibitory effects of cytokines present in the tumor microenvironment. Oncostatin-M (OSM) is an inflammatory cytokine produced by macrophages and T lymphocytes as well as tumor cells, it inhibits the proliferation and induces differentiation of a number of types of tumors. This study aimed to study OSM expression on both gene and protein levels. Methods:in vitro study done on thirty (OSCC) cases obtained from paraffin blocks and ten normal epithelial tissues used as control. For each case immunohistochemical examination of OSM protein intissues as well as quantitative real time polymerase chain reaction(RT-PCR) were done for determination of expression of both OSM gene and its specific receptor, finally results were statistically analyzed using ANOVA test

Issued also as CD

There are no comments on this title.

to post a comment.

Click on an image to view it in the image viewer

Local cover image