Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-diagnosis

Objectives & aim of work: to evaluate intra renal arterial resistivity index (RI) in primary hypertensive patient & its correlation with those of normotensive population. Background: Constant increase in the incidence of primary hypertension has made it necessary to have new markers for the early detection of hypertensive nephropathy. One of the markers that could be helpful in detecting functional alterations in renal hemodynamics is assessment of the renal resistivity index (RI) by using renal Doppler. Methods: We studied 50 patients with primary hypertension (Group-A), which comprised of 26 females and 24 males, with a mean age of 54.96 ± 9.73 years (38-70 years) with duration of hypertension range from 1 to 28 years with mean duration was 10.5600 ±7.14 years while A control group (Group-B) comprising of 50 healthy adult with normal hypertension, 28 females and 22 males with mean age of 49 ± 10.63 years (35-70 years) was also studied. The following parameters were studied in the two groups: age, sex, RI at upper, middle, lower intrarenal arteries and mean renal RI of both kidneys, duration of hypertension. Results: We found an increase in the mean RI in hypertensive patients versus normotensive one; the mean RI in Group-A was 0.60 ± 0.047 while it was 0.52± 0.05231 in Group-B (P< 0.05*). This increase in RI had a positive correlation with duration of the disease.Conclusion: The mean intra renal arterial resistivity index (RI) in hypertensive patient is significantly higher than those of normotensive one and increases throughout the duration of disease

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