Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics

Objectives The aim of the study was to compare intravenous lidocaine to intravenous pethidine in postoperative outcomes mainly pain control after cesarean delivery in terms of VAS system and time of first need for analgesia during the first 24 hrs postoperative . Methods A total of 200 pregnant women who are candidates for elective cesarean delivery under spinal anesthesia., all of those patients presented during the period of September 2017 till March 2018 to Kasr-Al Ainy hospital , divided into 2 equal groups: group A who was given bolus intravenous dose of 1 mg/kg lidocaine 2% and group B who was given pethidine 1mg/kg IV, in both groups the following was studied: efficacy in pain control through the VAS system and time of first need for analgesia during the first 24 hrs after cesarean delivery as well as return of bowel functions and the incidence of nausea and vomiting and other complications. Results Our results showed statistically significant difference between both groups regarding time of first need for analgesia postoperative (P-value > 0.038) with earlier need for analgesia in gp B (pethidine) compared to the gp A (lidocaine), pain score at 2,4 and 12 hrs , with the lidocaine gp feeling less pain at 2, 4 and 12 hrs compared to the pethidine gp. On the other hand, There was no statistically signficant difference between the two groups regarding ambulation time and return of bowel sounds Conclusion intravenous lidocaine given in a dose of 1 mg/kg is more effective than intravenous pethidine given in a dose of 1 mg/kg in postoperative pain control after cesarean delivery

Issued also as CD