Treatment outcome of patients with carcinoma of vulva NCI Cairo experience / Ahmed Mohey Eldin Maged Abdelhamid ; Supervised Mervat Hassan Elnaggar , Ehab Mostafa Elnakoury , Ehab Mohamed Ahmed Elkest

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Oncology-Clinical

Background: Treatment of patients with vulvar carcinoma is challenging for oncologists, owning to the low incidence of the disease and the poor level of evidence for different treatment modalities. Aim of the work: To analyze the treatment outcome and different prognostic factors of vulvar cancer that presented to NCI - Cairo University during the period between years 2001-2016. Patients and methods: This is a retrospective study involving patients with pathologically proven vulvar carcinoma, who presented to the National cancer institute, Cairo university during the period from January 2001 to December 2016. Data was retrieved from the patients{u2019} medical records. The collected data included the patients{u2019} names, age, menopausal status, comorbidities, obstetric history, performance status, pathological subtype, FIGO stage, grade, date and type of surgery, details of adjuvant treatment and response to treatment, side effects and complications of treatment, follow-up details and patterns of failure, salvage treatment and patient status at last follow up. Results and Conclusion: Notably patients with < 2 positive lymph nodes had better OS than patients {u2265} 2 positive lymph nodes, tumor size {u2264} 5 cm had better survival than > 5 cm, age {u2264} 69 years was associated better survival. Larger studies could also possibly shed more light on the optimal role and type of radiation therapy for vulvar carcinoma

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