The effect of preoperative prophylactic antimicrobials, normothermia and glycaemic control on the incidence of surgical site infections after exploratory laparotomy surgeries in 185 emergency hospitals, Cairo university : Prospective observational study / Ehab Tarek Fahmy; Supervised Jehan Ali Elkholy , Sahar Mohammed Mostafa Elshall , Antoni Adel Fahmy

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Anaesthesia

Background: Surgical site infection (SSI) is considered one of the most important complication after surgery. Severity of SSI ranges from superficial skin infection to life-threatening conditions such as severe sepsis, and SSIs are responsible for increased morbidity, mortality, hospital stay and economic burden associated with surgery. SSI incidence is increasing globally. CDC guidelines for prevention of surgical site infection 2017 including prophylactic antimicrobials, glycaemic control and normothermia perioperative, all of which the anaesthesiologist plays an important role in their application for every patient. In our study we measure the effect of application of these guidelines on the Exploratory laparotomies patients in operating theatres of emergency hospital 185 one of Cairo university hospitals (CUH). Methods and material: A 140 patients undergoing Exploratory laparotomies patients in operating theatres of emergency hospital 185 one of Cairo university hospitals (CUH) were included in this study, each patient was administrated antimicrobial prophylaxis 30 minutes before skin incision , underwent tight glycaemic control with random blood sugar measurement every 1 hour perioperative and every 12 hours for 48 hours postoperative and underwent temperature control perioperative with patient temperature measured and recorded every 1 hour along operation. Patients then followed for 30 days postoperative for assessment of SSI occurrence and for the patients who suffered from SSI culture and sensitivity

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