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Outcome of different sodium concentration fluids in rehydration of children with diabetic ketoacidosis / Shimaa Atef Mohamed Khalid ; Supervised Mona Hassan Hafez , Heba Mohamed Sharaf Eldin , Nora Elsaid Badawi

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Shimaa Atef Mohamed Khalid , 2018Description: 125 P. : charts ; 25cmOther title:
  • نتاج أستخدام تركيزات مختلفة من الصوديوم فى المحاليل العلاجية لحالات الحموضة الكيتونيه للأطفال المصابين بمرض السكر [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Objective: This study aimed to describe the effect of the use of 0.9% saline (NS) versus 0.45% saline (half NS) during fluid management of diabetic ketoacidosis (DKA) in children. Methods: This was a prospective, randomized, non blinded study that included 121 patients with moderate and severe diabetic ketoacidosis admitted in the Diabetes, Endocrinology & Metabolic Pediatric Unit (DEMPU) at Cairo University Children`s Hospital from April 2016 to April 2017. Results: The incidence of hyperchloremic acidosis was significantly less with the use of half normal saline compared to normal saline during the management of DKA (P value = 0.02) without adversely affecting other outcomes. Conclusions: Hyperchloremic acidosis can occur during management of DKA in patients receiving NS as post-bolus rehydration fluid. Alternatively, the use of half NS may result in a decrease in the incidence of hyperchloremic acidosis
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.Ph.D.2018.Sh.O (Browse shelf(Opens below)) Not for loan 01010110076289000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.Ph.D.2018.Sh.O (Browse shelf(Opens below)) 76289.CD Not for loan 01020110076289000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Objective: This study aimed to describe the effect of the use of 0.9% saline (NS) versus 0.45% saline (half NS) during fluid management of diabetic ketoacidosis (DKA) in children. Methods: This was a prospective, randomized, non blinded study that included 121 patients with moderate and severe diabetic ketoacidosis admitted in the Diabetes, Endocrinology & Metabolic Pediatric Unit (DEMPU) at Cairo University Children`s Hospital from April 2016 to April 2017. Results: The incidence of hyperchloremic acidosis was significantly less with the use of half normal saline compared to normal saline during the management of DKA (P value = 0.02) without adversely affecting other outcomes. Conclusions: Hyperchloremic acidosis can occur during management of DKA in patients receiving NS as post-bolus rehydration fluid. Alternatively, the use of half NS may result in a decrease in the incidence of hyperchloremic acidosis

Issued also as CD

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