The effect of oral pre-treatment by nicorandil on the outcome of PCI in patients with ACS / Dalia Shawky Abdelmoneim ; Supervised Essam Baligh Ewis , Hussein Heshmat Kassem
Material type: TextLanguage: English Publication details: Cairo : Dalia Shawky Abdelmoneim , 2018Description: 174 P. : charts , facsimiles ; 25cmOther title:- تأثير تناول عقار النيكورانديل عن طريق الفم فى مرحلة ما قبل البدء بالعلاج بالتدخل التاجى عن طريق الجلد فى المرضى الذين يعانون من متلازمة الشريان التاجى الحادة [Added title page title]
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Item type | Current library | Home library | Call number | Copy number | Status | Date due | Barcode | |
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Thesis | قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.04.M.Sc.2018.Da.E (Browse shelf(Opens below)) | Not for loan | 01010110076701000 | |||
CD - Rom | مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.04.M.Sc.2018.Da.E (Browse shelf(Opens below)) | 76701.CD | Not for loan | 01020110076701000 |
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Cai01.11.04.M.Sc.2018.Am.E The effects of antihypertensive agents on central blood pressure measured by automated blood pressure device in hypertensive Egyptian patients / | Cai01.11.04.M.Sc.2018.Ba.E Effect of tramadol on the heart / | Cai01.11.04.M.Sc.2018.Ba.E Effect of tramadol on the heart / | Cai01.11.04.M.Sc.2018.Da.E The effect of oral pre-treatment by nicorandil on the outcome of PCI in patients with ACS / | Cai01.11.04.M.Sc.2018.Da.E The effect of oral pre-treatment by nicorandil on the outcome of PCI in patients with ACS / | Cai01.11.04.M.Sc.2018.Dy.A Acute venous thromboembolic events in hospitalized patients : A Cairo University hospital registry / | Cai01.11.04.M.Sc.2018.Dy.A Acute venous thromboembolic events in hospitalized patients : A Cairo University hospital registry / |
Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Cardiology
Coronary artery disease (CAD) is considered to be the most common disease worldwide and has the highest mortality rate in the western countries. 1 In recent years, percutaneous coronary intervention (PCI) has become the principal means of revascularization in patients with CAD. 2-3 No reflow or slow flow occurs in 3-4% of all percutaneous coronary interventions. The current available approaches to prevent and treat no-reflow include IIBIIIA blockers, adenosine, nitroprusside, and mechanical thrombectomy aspiration devices. Nicorandil is an ATP sensitive potassium channel (KATP) open agent with the effect of nitrate. 4, 5 Intravenous nicorandil before PCI can significantly reduce the incidence of coronary slow flow after postoperative. 6, 7 nicorandil can antagonize ADP induced platelet aggregation, improve microcirculation in ischemic area and decrease no reflow phenomenon. 8 In our study, we have detected the effect of oral pre-treatment by nicorandil on the outcome of PCI in patients with ACS. The aim of the study: Primary was evaluation of post procedural no-reflow and slow flow phenomenon by evaluation TIMI flow and cTFC pre and post PCI and secondary was evaluation of peri-procedure myocardial infarction (MI) and one month major adverse cardiac events MACE
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