Bedtime versus morning insulin glargine in controlling blood glucose in children with type I diabetes using continuous glucose monitoring system / Radwa Ahmed Abdelhamid Shamma ; Supervised Ghada Mohammad Anwar , Noha Musa Azab , Marwa Farouk Mira
Material type:
- الوقت الأمثل لتناول الأنسولين جلارجين قبل النوم أو صباحا للتحكم فى نسبة السكر فى الدم للأطفال الذين يعانون من النوع الأول لمرض السكر باستخدام نظام الرصد المستمر للجلوكوز [Added title page title]
- Issued also as CD
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.28.Ph.D.2018.Ra.B (Browse shelf(Opens below)) | Not for loan | 01010110076656000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.28.Ph.D.2018.Ra.B (Browse shelf(Opens below)) | 76656.CD | Not for loan | 01020110076656000 |
Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Pediatrics
Introduction: Type 1 diabetes mellitus (T1DM), one of the most common chronic diseases in childhood, is caused by insulin deficiency following destruction of the insulin-producing pancreatic beta cells.(CGM) systems are an emerging technology that allows frequent glucose measurements to monitor glucose trends in real time. Two types of CGM systems can be defined: retrospective systems and real-time systems. Aim of Work: To compare GCM readings and metabolic control in type 1 diabetic children receiving bedtime versus morning insulin glargine dose. Methods: A cross sectional observational study was conducted on 30 pediatric patients with T1DM receiving insulin glargine(19 on bedtime glargine and 11 on morning glargine).CGM sensor was applied subcutaneously to the included patients for a period of 3- 5 days, then the readings of CGM wereinterpretedfor their glycemic control. Results: There was statistically significant difference between both groups regarding the occurrence of hypoglycemia (Nocturnal), 13 patients on (bedtime glargine) developed nocturnal hypoglycemia compared to 4 patients on (morning glargine) (p=0.016).The use of CGM in glycemic control is associated with reduction in HbA1C (p<0.001)
Issued also as CD
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