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Formulation of non steroidal anti-inflammatory drug in topical dosage form / Dina Ahmed Mostafa Shaaban ; Supervised Alia Badawi , Doaa Ahmed Elsetouhy , Boushra Mohamed Elhoussieny

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Dina Ahmed Mostafa Shaaban , 2018Description: 129 P. : charts , facsimiles ; 25cmOther title:
  • صياغة عقار مضاد للالتهاب غير استيرويدى في شكل صيدلى سطحى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics Summary: Non-steroidal anti-inflammatory drugs are widely used for treatment of pain and inflammation, all classic NSAIDs inhibit COX-1 and COX-2, causing undesirable side effects such as gastric ulceration, altering platelet function and renal toxicity. Topical drug delivery systems are attractive routes for administration of NSAIDs, as they overcome gastrointestinal side effects and give local therapeutic effect. Lornoxicam, the drug of choice in this study, is a potent NSAID that belong to oxicams, it has short half-life, which require repeated uptake. In addition, lornoxicam has poor aqueous solubility leading to poor bioavailability
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.M.Sc.2018.Di.F (Browse shelf(Opens below)) Not for loan 01010110076873000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.08.M.Sc.2018.Di.F (Browse shelf(Opens below)) 76873.CD Not for loan 01020110076873000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics

Non-steroidal anti-inflammatory drugs are widely used for treatment of pain and inflammation, all classic NSAIDs inhibit COX-1 and COX-2, causing undesirable side effects such as gastric ulceration, altering platelet function and renal toxicity. Topical drug delivery systems are attractive routes for administration of NSAIDs, as they overcome gastrointestinal side effects and give local therapeutic effect. Lornoxicam, the drug of choice in this study, is a potent NSAID that belong to oxicams, it has short half-life, which require repeated uptake. In addition, lornoxicam has poor aqueous solubility leading to poor bioavailability

Issued also as CD

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