The effect of telephone based follow-up on adherence, efficacy, and toxicity of oral capecitabine based-chemotherapy in Egyptian patients with colorectal and gastric cancer / Hend Kamal Maamoun Eldeib ; Supervised Nirmeen Sabry , Maggie M. Abbassi , Salem Eid Salem
Material type: TextLanguage: English Publication details: Cairo : Hend Kamal Maamoun Eldeib , 2018Description: 180 P. : facsimiles ; 25cmOther title:- تأثير المتابعة عن طريق الهاتف على الالتزام: و الكفاءة: و سمية العلاج الكيميائى القائم على الكابيستابين عن طريق الفم فى المرضى بسرطان القولون و المستقيم و المعدة المصريين [Added title page title]
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Item type | Current library | Home library | Call number | Copy number | Status | Date due | Barcode | |
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Thesis | قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.08.08.M.Sc.2018.He.E (Browse shelf(Opens below)) | Not for loan | 01010110077227000 | |||
CD - Rom | مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.08.08.M.Sc.2018.He.E (Browse shelf(Opens below)) | 77227.CD | Not for loan | 01020110077227000 |
Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutics
Background: Adherence and safety challenges appeared with the use of oral chemotherapeutic agents like capecitabine, necessitating the implementation of a more focused follow-up for patients receiving these agents. Objective: This study aimed to evaluate the efficacy of telephone-based follow-up on patients{u2019} adherence to capecitabine, capecitabine safety, efficacy and health service utilization in colorectal, and gastric cancer patients. Setting: Two hundred and four colorectal and gastric cancer patients were recruited from National cancer institute, Cairo, Egypt. Methods: This was a prospective randomized controlled open label study on patients treated with capecitabine-based chemotherapy regimens. Patients were randomly allocated to either control (N = 98) group (receiving the chemotherapy with the standard usual care) or the intervention (N=106) group (receiving the chemotherapy, standard usual care, and 2 telephone calls in each treatment cycle by a pharmacist). The Main outcome measure focused on patients{u2019} adherence (assessed using tablet count technique), and safety (assessed using common terminology Criteria for Adverse Events (CTCAE) version 4.03)
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