Evaluation of different treatment modalities in the management of persistent pulmonary hypertension in term and near term neonates / Mustafa Mahmoud Mohamed Tawfik ; Supervised Fatma Alzahraa Mostafa Gomaa , Amira Ahmed Mohamed Elgammal , Antoine Fakhry Abdelmassih
Material type:
- تقييم الطرق العلاجية المختلفة فى علاج ارتفاع ضغط الشريان الرئوى فى الاطفال حديثى الولادة [Added title page title]
- Issued also as CD
Item type | Current library | Home library | Call number | Copy number | Status | Barcode | |
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.28.M.Sc.2018.Mu.E (Browse shelf(Opens below)) | Not for loan | 01010110077664000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.28.M.Sc.2018.Mu.E (Browse shelf(Opens below)) | 77664.CD | Not for loan | 01020110077664000 |
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Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics
Background: Persistent pulmonary hypertension of the newborn (PPHN) is a cardiopulmonary disorder characterized by elevated pulmonary vascular resistance with resultant shunting of pulmonary blood to the systemic circulation. Diagnosis of PPHN is usually made by echocardiography. Management of the disease includes treatment of underlying causes, sedation, and analgesia, maintenance of adequate blood pressure, and ventilator and pharmacologic measures to increase pulmonary vasodilatation, and normalize blood pH. Other treatment options include (ECMO) and inhaled nitric oxide (iNO). Aim of work: The main aim is to evaluate the different inotropes and pulmonary vasodilators in managing PPHN in term and near term neonates. Patients and methods: A final number of 41 neonates presented with PPHN, fulfilling inclusion criteria, in the period from February 2018 till the end of July 2018 to the (NICU) of Cairo university children Hospital. They were categorized according to the main drug used (milrinone, sildenafil or dobutamine) into three groups and compared to each other regarding improvement in oxygen saturation, oxygenation index (OI) and echocardiographic parameters
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