Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine

Background : The mainstay of modern intensive care medicine is to guarantee the function of the cardiorespiratory system. Extracorporeal membrane oxygenation (ECMO) represents nowadays the only therapy capable of completely replacing these vital functions.Aim of the work: to document and analyze the data and patients who received ECMO support in the critical care department -Cairo University from 2014 to 2017.Methods: Twenty-seven patients received ECMO support were enrolled in our study. Twenty three patients received Veno-venous (V-V) ECMO, four patients received Veno-arterial (V-A) ECMO and four patients received hybrid support. All patients were subjected to full history taking and clinical examination before ECMO, Full blood chemistry, blood gases, Chest X ray and Echocardiography before and after connection to ECMO. All hemodynamic variables, ECMO variables and complications were collected and analyzed.Results: The overall survival rate in our patients was 29.6%, mortality during ECMO support was 63% and mortality after decannulation was 7.4%. The average duration of ECMO run was 14.6 day and the average length of ICU stay was 20.4 day. The average duration of V-A ECMO run was 4.5 day. The average duration of V-V ECMO run was 16.4 day. In our study, we used V-V ECMO as a respiratory support for total 23 patients with ARDS due to either bacterial infection, viral infection, aspiration, trauma or toxins. The overall survival rate in our V-V group was 35 %

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