Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Critical Care Medicine

Background: the assessment of how different lung regions respond to therapeutic interventions over time is reduced to guess work. The Electrical Impedance Tomography, PulmoVista 500 lets you continuously and directly observe ventilation in different lung regions, facilitating the development of individualized therapy. Objectives: Evaluation of regional lung ventilation by electrical impedance tomography in different lung pathologies undergoing mechanical ventilation and monitoring differences in regional lung ventilation during different modes of ventilation: Assisted volume controlled, assisted pressure controlled and pressure support. Patient and method: Mechanically ventilated Patients were randomly connected on the following modes of mechanical ventilation as assisted volume and pressure control in initial/maintainace phase and three levels of pressure support (20cmH2O, 10cmH2O and10cmH2O), then assess regional lung ventilation by EIT in ROI EELI change, then compare between A/VC and A/PC in ROI EELI change, and also compare between the 3 level of pressure support in ROI EELI change. Intervention: no intervention. Results: EELI changes in the Rt upper quadrant were significantly higher in A/VC than A/PC (mean ± SD .97±3.79 vs. -1.48-±4.53, p .015), while there were no statistically significant difference between both modes regarding other lung quadrants and EELI changes in the Rt lower quadrant and left lower quadrants were significantly higher using PS (15 cmH2O) than PS (20cmH2O) and PS (10cmH2O) (mean ± SD 1.68± 1.93 vs. 1.15±3.91 vs. -.88-±4.41, p 0.007) (mean ± SD 1.35±1.90 vs. 68±3.01 vs. 18-±4.37, p < 0.001) respectively

Issued also as CD