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Probes for some antimicrobials : Synthesis, characterization, and applicationin pharmaceutical analysis / Marwa Soliman Abdelhamid Elhamshary ; Supervised Samir Elmoghazy , Hala Aleasa , Marwa Ahmed Fouad

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Marwa Soliman Abdelhamid Elhamshary , 2018Description: 252 P. : charts ; 25cmOther title:
  • أقطاب لبعض مضادات الميكروبات : التوليف: التوصيف والتطبيق في التحليل الصيدلي [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry Summary: The present thesis describes the investigation of three fluoroquinolones, namely, Norfloxacin, Levofloxacin and Lomefloxacin via three techniques through two main approaches. First, is complexation of the investigated drugs with lanthanides as samarium, terbium and lanthanum and detecting the formed complex whether spectrophotometrically or spectrofluorimetrically.This approach applies the multivariate analysis for the detection of the optimal blend of factors affecting this complexation over two phases to build the model; screening and optimization, followed by verification and validation of the developed models. Second approach is constructing potentiometric sensors for the nominated fluoroquinolones based on tetraphenylborate as ion-exchanger casted with PVC and DOP and plasticizer followed by the study of the performance characteristics of the electrodes
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2018.Ma.P (Browse shelf(Opens below)) Not for loan 01010110077964000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.05.Ph.D.2018.Ma.P (Browse shelf(Opens below)) 77964.CD Not for loan 01020110077964000

Thesis (Ph.D.) - Cairo University - Faculty of Pharmacy - Department of Pharmaceutical Chemistry

The present thesis describes the investigation of three fluoroquinolones, namely, Norfloxacin, Levofloxacin and Lomefloxacin via three techniques through two main approaches. First, is complexation of the investigated drugs with lanthanides as samarium, terbium and lanthanum and detecting the formed complex whether spectrophotometrically or spectrofluorimetrically.This approach applies the multivariate analysis for the detection of the optimal blend of factors affecting this complexation over two phases to build the model; screening and optimization, followed by verification and validation of the developed models. Second approach is constructing potentiometric sensors for the nominated fluoroquinolones based on tetraphenylborate as ion-exchanger casted with PVC and DOP and plasticizer followed by the study of the performance characteristics of the electrodes

Issued also as CD

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