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The prognostic value of Interim PET in pediatric hodgkin lymphoma, National cancer institute, Egypt 2011-2015 / Sally Mahfouz Abdelnaby ; Supervised Lobna Mohammed Shalaby , Reham Abdelaziz Khedr , Hoda Fathy Elsayed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Sally Mahfouz Abdelnaby , 2018Description: 103 P. : charts ; 25cmOther title:
  • كمؤسر فى علاج سرطان الأطفال الليمفاوى هودجيكن بالمعهد القومى لللاورام: مصر 2011-2015 PET CT تقييم استخدام المسح الذرى [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology Summary: Background: Hodgkin's lymphoma (HL) is a highly curable malignant disease. Risk-adapted therapy for children with HL is directed toward high survival, minimal toxicity and optimal quality of life. 18F-FDG PET is a well-established surrogate for tumor chemosensitivity early during therapy. The ongoing PET-adaptive clinical trials are testing the hypothesis that a decision can reliably be made on escalating or deescalating therapy based on interim PET results. Aims: In this study we aimed to identify the prognostic role of interim PET in predicting the prognosis of HL in our center. Methods: This is a retrospective, single center study where a total of 140 patients with newly diagnosed Hodgkin lymphoma were enrolled. Only 83 patients were eligible for analysis of interim PET. PET scan was performed at baseline and after two cycles of chemotherapy. Treatment was not changed according to the results of the interim scan. PET scans reports was used using the Deauville five-point scale, blinded to treatment outcome
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.05.M.Sc.2018.Sa.P (Browse shelf(Opens below)) Not for loan 01010110077855000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.05.M.Sc.2018.Sa.P (Browse shelf(Opens below)) 77855.CD Not for loan 01020110077855000

Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Pediatric Oncology

Background: Hodgkin's lymphoma (HL) is a highly curable malignant disease. Risk-adapted therapy for children with HL is directed toward high survival, minimal toxicity and optimal quality of life. 18F-FDG PET is a well-established surrogate for tumor chemosensitivity early during therapy. The ongoing PET-adaptive clinical trials are testing the hypothesis that a decision can reliably be made on escalating or deescalating therapy based on interim PET results. Aims: In this study we aimed to identify the prognostic role of interim PET in predicting the prognosis of HL in our center. Methods: This is a retrospective, single center study where a total of 140 patients with newly diagnosed Hodgkin lymphoma were enrolled. Only 83 patients were eligible for analysis of interim PET. PET scan was performed at baseline and after two cycles of chemotherapy. Treatment was not changed according to the results of the interim scan. PET scans reports was used using the Deauville five-point scale, blinded to treatment outcome

Issued also as CD

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