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Validation of a prognostic score to predict short-term mortality in patients with acute-on-chronic liver failure / Mahmoud Sherbiny Ahmed Sherbiny ; Supervised Rabab Fouad Emam Omar , Ahmed Aly Elray , Hesham Ibrahim Elmakhzangy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mahmoud Sherbiny Ahmed Sherbiny , 2018Description: 147 P. : charts ; 25cmOther title:
  • التقييم الاستباقى للتنبؤ بحدوث الوفاة على المدى القصير فى مرضى تليف الكبد الذين يعانون من فشل حاد [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine Summary: Back ground: Acute-on-chronic liver failure (ACLF) is a syndrome characterized by acute decompensation (AD) of cirrhosis, organ/system failure(s) and high short-term mortality. Objectives: To assess cirrhotic patients hospitalized for an AD for the diagnosis and grading of ACLF and to predict short-term prognosis according to EASL-CLIF consortium to guide therapeutic decision. Patients and methods: 120 cirrhotic patients with AD were prospectively included. The patients were divided into ACLF and no ACLF patients according to EASL-CLIF Definition of ACLF. All patients followed up for 3 months from inclusion or mortality whichever was earlier. The Prognostic scores like CLIF-SOFA, CLIF-C OF, MELD, MELD-Na and child-pugh scores were evaluated for their ability to predict 28-d and 90-d mortality in all patients and patients with ACLF using AUROC. The CLIF»C AD score was evaluated for AD without ACLF
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.33.Ph.D.2018.Ma.V (Browse shelf(Opens below)) Not for loan 01010110077875000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.33.Ph.D.2018.Ma.V (Browse shelf(Opens below)) 77875.CD Not for loan 01020110077875000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine

Back ground: Acute-on-chronic liver failure (ACLF) is a syndrome characterized by acute decompensation (AD) of cirrhosis, organ/system failure(s) and high short-term mortality. Objectives: To assess cirrhotic patients hospitalized for an AD for the diagnosis and grading of ACLF and to predict short-term prognosis according to EASL-CLIF consortium to guide therapeutic decision. Patients and methods: 120 cirrhotic patients with AD were prospectively included. The patients were divided into ACLF and no ACLF patients according to EASL-CLIF Definition of ACLF. All patients followed up for 3 months from inclusion or mortality whichever was earlier. The Prognostic scores like CLIF-SOFA, CLIF-C OF, MELD, MELD-Na and child-pugh scores were evaluated for their ability to predict 28-d and 90-d mortality in all patients and patients with ACLF using AUROC. The CLIF»C AD score was evaluated for AD without ACLF

Issued also as CD

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