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Role of apelin in the pathophysiology of esophageal varices complicating chronic HCV infection in Egyptian patients / Lamyaa Hany Abdellatif Soliman ; Supervised Iman Refaat Elmahgoub , Rania Ahmed Zayed , Fadwa Saied Abdelazim

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Lamyaa Hany Abdellatif Soliman , 2018Description: 150 P. : charts ; 25cmOther title:
  • دور الابلين في الفيسيولوجية المرضية لدوالي المريء في مرضى الالتهاب الكبدي الوبائي سي المصريين [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology Summary: Introduction and aim of work: Portal hypertension and esophageal varices formation complicating chronic HCV infection are considered the most devastating side effects of chronic liver disease owing to the bleeding-related mortality. Angiogenesis is the hallmark of their pathogenesis. Apelin is one of the recently identified angiogenic and fibrogenic peptide of wide distribution in various tissues. We studied apelin gene expression and SNP (rs3761581) of the apelin gene in chronic HCV patients to assess their association with the degree of hepatic fibrosis, esophageal varices formation as well as the grade of esophageal varices
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.Ph.D.2018.La.R (Browse shelf(Opens below)) Not for loan 01010110078511000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.07.Ph.D.2018.La.R (Browse shelf(Opens below)) 78511.CD Not for loan 01020110078511000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Clinical and Chemical Pathology

Introduction and aim of work: Portal hypertension and esophageal varices formation complicating chronic HCV infection are considered the most devastating side effects of chronic liver disease owing to the bleeding-related mortality. Angiogenesis is the hallmark of their pathogenesis. Apelin is one of the recently identified angiogenic and fibrogenic peptide of wide distribution in various tissues. We studied apelin gene expression and SNP (rs3761581) of the apelin gene in chronic HCV patients to assess their association with the degree of hepatic fibrosis, esophageal varices formation as well as the grade of esophageal varices

Issued also as CD

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