Comparative study between endorectal magnetic resonance imaging and transrectal ultrasound in the diagnosis and staging of prostatic cancer / Samah Farouk Abdullah ; supervised Mamdouh Mahfouz Ali , Maha Hussein Helal , Alaa ElDin Wafik Meshref

Thesis (PH.D.) - Cairo University - Faculty Of Medicine - Department Of Radio-diagnosis

Cancer prostate is an important and escalating health problem in both the developed and developing countriesIt is a potentially curable disease especially in its early stages and hence carries a low morbidityIt was our aim to investigate the potential of one of the oldest and most popular imaging modalitagainst a more advanced but less used imaging modality in this field , ieTRUS and En MRIIn our study of 30 patients we found out that the majority of our cases were very advancedYet still with the limitations met with in this study (such as the small sample size and the lack of true pathological specimens) we managed to pin point the limits and potentials of each modality ; TRUS seemed to be less accurate than En MRI in eliciting PZ lesions correctlyHowever both were blind to inner gland lesionsAlthough both modalities might have shown humble staging accuracy rates yet En MRI has seen closer in itsstaging to that of pathology than TRUSThis may be owed to the high accuracy of En MRI in eliciting ECE , SV infiltration and regional LN enlargementBy combining En MRI with Dynamic Contrast Enhanced MRI the latter seemed to increase En MRI's accuracy in detection and staging of prostate tumors even in the inner glandHowever , do to the limitations of our study it may be more beneficial and scientifically yielding if the study was performed on a larger scale and was confirmed with surgical pathological samples

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