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Aging changes of the testis in albino rat : Light, electron microscopic and immunohistochemical study / Sally Mohsen Mohamed Hussein ; Supervised Zaizafon Hussein Badawy , Amina Borhamy Elfadaly , Ahmed Galal Metawea

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Sally Mohsen Mohamed Hussein , 2019Description: 209 P. : charts , facsimiles ; 25cmOther title:
  • تأثير تقدم العمر على خصية الفأر الأبيض : دراسة بالميكروسكوب الضوئي والميكروسكوب الٳلكتروني وهيستوكيميائية مناعية [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anatomy Summary: Aging has a deleterious effect on the morphology of the male reproductive system which might, in turn, lead to changes in spermatogenesis and consequently, decrease in both quality and quantity of spermatozoa. The present study elucidated the histological and ultrastructural changes of testes of adult albino rats during aging and applied morphometric measures to obtain quantitative data for these changes. The oxidative and antioxidative markers of aged testes were also assessed. The results documented the presence of age-related regressive structural changes of the testis accompanied with an increase in the apoptosis and a decrease in the proliferative capacity. The biochemical results gave evidence of an imbalance between the oxidative damage and the antioxidant defense indicating increased oxidative stress of aged testis
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.02.Ph.D.2019.Sa.A (Browse shelf(Opens below)) Not for loan 01010110078763000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.02.Ph.D.2019.Sa.A (Browse shelf(Opens below)) 78763.CD Not for loan 01020110078763000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anatomy

Aging has a deleterious effect on the morphology of the male reproductive system which might, in turn, lead to changes in spermatogenesis and consequently, decrease in both quality and quantity of spermatozoa. The present study elucidated the histological and ultrastructural changes of testes of adult albino rats during aging and applied morphometric measures to obtain quantitative data for these changes. The oxidative and antioxidative markers of aged testes were also assessed. The results documented the presence of age-related regressive structural changes of the testis accompanied with an increase in the apoptosis and a decrease in the proliferative capacity. The biochemical results gave evidence of an imbalance between the oxidative damage and the antioxidant defense indicating increased oxidative stress of aged testis

Issued also as CD

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