header
Image from OpenLibrary

Assessment of serum and tissue levels of IL-17 in lichen planus / Marwa Kadry Anwar ; Supervised Sara Bahaa Eldin , Dina Elsharkawy ,Olfat Shaker

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Marwa Kadry Anwar , 2019Description: 113 P. : charts , facsimiles ; 25cmOther title:
  • تقييم مستوى الإنترلوكين 17 في الدم و الأنسجة مرض الحزاز [Added title page title]
Subject(s): Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology Summary: Background: Lichen planus (LP) is a chronic inflammatorydisease affecting the skin, mucous membranes, scalp and nails. Interleukin (IL)-17 is a proinflammatory cytokine involved in the pathogenesis of several autoimmune and inflammatory disorders. Aim of work: To measure the serum and tissue levels of IL-17 in LP patients in comparison to controls, in order to assess the possible role of IL-17 in the pathogenesis of LP. Methods: This study included 30 LP patients and 30 age and sex matched healthy controls. Blood samples and skin biopsies were taken from all participants for evaluation of serum and tissue IL-17 levels by Enzyme linked immunosorbent assay (ELISA). Results: Serum and tissue IL-17 were significantly higher in patients than controls (p=0.000 for both). A statistically significant positive correlation was found between serum IL-17 and extent of the disease (r=0.584, p= 0.001)
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.10.M.Sc.2019.Ma.A (Browse shelf(Opens below)) Not for loan 01010110079073000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.10.M.Sc.2019.Ma.A (Browse shelf(Opens below)) 79073.CD Not for loan 01020110079073000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Dermatology and Venerology

Background: Lichen planus (LP) is a chronic inflammatorydisease affecting the skin, mucous membranes, scalp and nails. Interleukin (IL)-17 is a proinflammatory cytokine involved in the pathogenesis of several autoimmune and inflammatory disorders. Aim of work: To measure the serum and tissue levels of IL-17 in LP patients in comparison to controls, in order to assess the possible role of IL-17 in the pathogenesis of LP. Methods: This study included 30 LP patients and 30 age and sex matched healthy controls. Blood samples and skin biopsies were taken from all participants for evaluation of serum and tissue IL-17 levels by Enzyme linked immunosorbent assay (ELISA). Results: Serum and tissue IL-17 were significantly higher in patients than controls (p=0.000 for both). A statistically significant positive correlation was found between serum IL-17 and extent of the disease (r=0.584, p= 0.001)

Issued also as CD

There are no comments on this title.

to post a comment.