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Effect of curcumin on brain injury induced by intestinal ischemia-reperfusion in mice / Noha Farid Elshazly ; Supervised Samira Saleh Mostafa , Azza Sayed M. Awad , Nesrine Salah Eldin

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Noha Farid Elshazly , 2019Description: 126 P. : charts , facsimiles ; 25cmOther title:
  • تأثير الكركمين في إصابات الدماغ الناتجة عن حبس الدم الموضعي وإعاده الترويه في أمعاء الفئران [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology Summary: Intestinal ischemia/reperfusion (II/R) induces a systemic inflammatory response and releases harmful substances that may affect the function and integrity of distant organs such as brain, lung, liver, and kidney. Oxidative stress and inflammatory cytokines are among the key mechanisms of brain tissue damage after intestinal ischemia reperfusion. Therefore improving the redox balance, abating the inflammatory cytokines are the most important goals to attenuate damage after intestinal ischemia reperfusion. Curcumin (CUR), the turmeric is the common name for Curcuma longa, exhibit several pharmacologic properties as anti-inflammatory and antioxidant agent and exert neuroprotective effects in a variety of neurodegenerative disorders including Alzheimer{u2019}s disease, Parkinson{u2019}s disease, and cerebral ischemia by crossing the blood{u2013}brain barrier Moreover, Curcumin is known to play a vital role against oxidative-stress-mediated pathological conditions. , protect biomembranes against peroxidative damage
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.09.M.Sc.2019.No.E (Browse shelf(Opens below)) Not for loan 01010110079460000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.08.09.M.Sc.2019.No.E (Browse shelf(Opens below)) 79460.CD Not for loan 01020110079460000

Thesis (M.Sc.) - Cairo University - Faculty of Pharmacy - Department of Pharmacology and Toxicology

Intestinal ischemia/reperfusion (II/R) induces a systemic inflammatory response and releases harmful substances that may affect the function and integrity of distant organs such as brain, lung, liver, and kidney. Oxidative stress and inflammatory cytokines are among the key mechanisms of brain tissue damage after intestinal ischemia reperfusion. Therefore improving the redox balance, abating the inflammatory cytokines are the most important goals to attenuate damage after intestinal ischemia reperfusion. Curcumin (CUR), the turmeric is the common name for Curcuma longa, exhibit several pharmacologic properties as anti-inflammatory and antioxidant agent and exert neuroprotective effects in a variety of neurodegenerative disorders including Alzheimer{u2019}s disease, Parkinson{u2019}s disease, and cerebral ischemia by crossing the blood{u2013}brain barrier Moreover, Curcumin is known to play a vital role against oxidative-stress-mediated pathological conditions. , protect biomembranes against peroxidative damage

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