Impact of direct acting anti HCV drugs (DAAs) on renal function indices in patients with chronic Hepatitis C virus (HCV) infection / Amaal Marzouk Abdelwahab ; Supervised Mohammad Elsayed Soliman , Shereen Abdelalem Mohammed , Zeinab Abdellatif Mahmoud
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- تأثير أدوية علاج فيروس الالتهاب الكبدي الوبائي المزمن (سي) ذات التأثير المباشر علي مؤشرات وظائف الكلي في مرضي عدوي فيروس الالتهاب الكبدي الوبائي المزمن سي [Added title page title]
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قاعة الرسائل الجامعية - الدور الاول | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.33.M.Sc.2019.Am.I (Browse shelf(Opens below)) | Not for loan | 01010110079619000 | ||
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مخـــزن الرســائل الجـــامعية - البدروم | المكتبة المركزبة الجديدة - جامعة القاهرة | Cai01.11.33.M.Sc.2019.Am.I (Browse shelf(Opens below)) | 79619.CD | Not for loan | 01020110079619000 |
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Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Tropical Medicine
Background and aim Hepatitis C virus (HCV) infection is a global health problem. The changes in renal function indices after receiving direct acting antiviral drugs (DAAs) in chronic HCV infected patients with normal renal functions is not well defined. The aim of our study is to evaluate the changes in renal function indices in Egyptian patients with chronic HCV infection following treatment with DAAs- based therapy. Patients and methods This is a prospective study included 159 Egyptian patients with chronic HCV infection who received DAAs-based therapy at Viral Hepatitis Specialized Treatment Center at Kasr Al-Ainy University Hospital according to the guidelines of the National Committee for Control of Viral Hepatitis (NCCVH) in the period from October 2017 to November 2018. The received regimens were SOF/DAC±RBV and one patient received Querevo/SOF/RBV. Relevant laboratory tests were obtained before initiation of therapy, after 4 and 8 weeks of therapy, at the end of treatment (EOT) and 12 weeks after EOT; SVR12significance
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