Evaluation of a simplified technique for excision of non-palpable (screen - detected) breast cancer / Aya Muhammad Abdelfattah Alamrawy ; Supervised Emad Khallaf , Muhammad Almarzouky , Lamiaa Adel

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of General Surgery

Background: Breast cancer is the most common type of cancer and the second leading cause of cancer deaths among women. Early-stage diagnosis through screening programs increases the chances of survival and, therefore, reduces mortality rates.through accurate localization and Excision of early non palpable lesions either for diagnostic or therapeutic purposes. Objective: Evaluation of the accuracy wire localization technique in excision of non palpable lesion with optimum margin. Methods: Fourty female patients with screen detected abnormalities were subjected to wire localization technique either for diagnostic or therapeutic purpose. All specimens were subjected to specimen mammography. Patients with preoperative diagnosis as cancer had intraoperative Sentinel lymph node biopsy and frozen section for margin assessment. patients without preoperative diagnosis specimens were sent for paraffin section and then managed according to the results. Results: The rexcision rate was (3/46) 6.5%, 2 cases were due to infiltrated margin (4.3%) and one case was due to missed hook (2.2%). The average size of the surgically excised specimen was 83.9 cc. Conclusion: Despite of the larger average size of the specimen lower rates of infiltrated margin than other studies due to adequate preoperative workup, the use of intraoperative frozen sections

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