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Evaluation of right ventricular functions in patients with ischemic cardiomyopathy by speckle tracking echocardiograph / Dina Mohamed Yousry Ahmed ; Supervised Wafaa Anwar Elaroussy , Reham Mohamed Darweesh , Abdalla Amin Selim Elagha

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Dina Mohamed Yousry Ahmed , 2019Description: 154 P. : facsimiles ; 25cmOther title:
  • تقييم وظائف البطين الأيمن لدى مرضى أعتلال عضلة القلب الأحتشائى بإستخدام تقنية المسار النقطى بالموجات الفوق صوتية على القلب [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Cardiology Summary: Background Assessment of right ventricular (RV) function has a paramount importance in patients with ischemic cardiomyopathy. Conventional (2D) 2-dimensional determination of RV function is often qualitative. Speckle tracking echocardiography (STE) is a promising tool in assessing regional and global RV deformation in terms of amplitude and timing. We thought to evaluate RV functions and establish the prevalence of RV dysfunction, defined as TAPSE{u2264}16 mm in patients with ischemic heart disease (IHD) and left ventricular (LV) systolic dysfunction, using STE. Methods we prospectively studied 50 patients with the diagnosis of IHD and LV systolic dysfunction (EF< 50%) who underwent trans-thoracic echocardiography. Comprehensive assessment of the RV as regards dimensions (EDA, ESA, basal, mid, longitudinal dimensions, RVOT proximal and distal, and RV free wall thickness), conventional systolic (TAPSE, FAC, S', RV MPI) and diastolic parameters (E/A, E/E', DT) were measured. RV Global longitudinal strain (GLS) and free wall RV peak systolic strains (RV FW PSS) as well as LV GLS were measured by using STE. Right and left ventricular peak systolic strain rate (RV SRs, LV SRs) as well as early diastolic strain rate (RV SRe, LV SRe) were also measured. Results There was no agreement between the measurement of RV longitudinal systolic function by TAPSE compared to RV FW PSS (Kappa 0.063, p 0.2). MPI was the only conventional parameter measured by 2D echocardiography that correlated with RV GLS (r = 0.315, p = 0.026). Further evaluation of RV function by strain rate showed that RV SRs was significantly lower (r = 0.631, p < 0.001), and RV SRe was significantly higher (r = -0.346, p = 0.014) in ICM patients having normal RV systolic function by RV FW PSS, considering the unit of systolic strain and strain rate is negative, a negative correlation indicates that the lower parameter correlated, the better the RV function by strain and strain rate and vice versa
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.04.Ph.D.2019.Di.E (Browse shelf(Opens below)) Not for loan 01010110079708000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.04.Ph.D.2019.Di.E (Browse shelf(Opens below)) 79708.CD Not for loan 01020110079708000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Cardiology

Background Assessment of right ventricular (RV) function has a paramount importance in patients with ischemic cardiomyopathy. Conventional (2D) 2-dimensional determination of RV function is often qualitative. Speckle tracking echocardiography (STE) is a promising tool in assessing regional and global RV deformation in terms of amplitude and timing. We thought to evaluate RV functions and establish the prevalence of RV dysfunction, defined as TAPSE{u2264}16 mm in patients with ischemic heart disease (IHD) and left ventricular (LV) systolic dysfunction, using STE. Methods we prospectively studied 50 patients with the diagnosis of IHD and LV systolic dysfunction (EF< 50%) who underwent trans-thoracic echocardiography. Comprehensive assessment of the RV as regards dimensions (EDA, ESA, basal, mid, longitudinal dimensions, RVOT proximal and distal, and RV free wall thickness), conventional systolic (TAPSE, FAC, S', RV MPI) and diastolic parameters (E/A, E/E', DT) were measured. RV Global longitudinal strain (GLS) and free wall RV peak systolic strains (RV FW PSS) as well as LV GLS were measured by using STE. Right and left ventricular peak systolic strain rate (RV SRs, LV SRs) as well as early diastolic strain rate (RV SRe, LV SRe) were also measured. Results There was no agreement between the measurement of RV longitudinal systolic function by TAPSE compared to RV FW PSS (Kappa 0.063, p 0.2). MPI was the only conventional parameter measured by 2D echocardiography that correlated with RV GLS (r = 0.315, p = 0.026). Further evaluation of RV function by strain rate showed that RV SRs was significantly lower (r = 0.631, p < 0.001), and RV SRe was significantly higher (r = -0.346, p = 0.014) in ICM patients having normal RV systolic function by RV FW PSS, considering the unit of systolic strain and strain rate is negative, a negative correlation indicates that the lower parameter correlated, the better the RV function by strain and strain rate and vice versa

Issued also as CD

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