header
Image from OpenLibrary

SALL4 gene expression in acute myeloid leukemia / Fatma Mahmoud Ibraheem ; Supervised Ragia Hussein Badawy , Naglaa Moustafa Hassan , Mahmoud Aly Ayoub

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Fatma Mahmoud Ibraheem , 2017Description: 158 P. : charts , facsimiles ; 25cmOther title:
  • ظهور جين السول فور فى حالات سرطان الدم الميودي الحاد [Added title page title]
Subject(s): Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology Summary: SALL4 gene was aberrantly expressed in many leukemia cell lines and primary leukemia cells of acute myeloid leukemia (AML). The aim of this study was to investigate the expression level of the gene and its clinical significance in patients with acute myeloid leukemia (AML). Quantitative real-time PCR (qrt-PCR) was performed to detect the expression level of SALL4 mRNA in the bone marrow or peripheral blood samples from 52 AML and 10 control samples. The results indicated that the expression level of SALL4 in AML (median: 2.0 RQ) was obviously higher than that in controls (media: 1 RQ) with p value: 0.001. There was no statistically significant difference between cases and control in SALL4 gene expression with the age, sex, WBC count, Hb concentration, platelet count, chromosomal abnormalities of AML patients, FAB and WHO classification (P > 0.05)
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.03.Ph.D.2017.Fa.S (Browse shelf(Opens below)) Not for loan 01010110080047000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.03.Ph.D.2017.Fa.S (Browse shelf(Opens below)) 80047.CD Not for loan 01020110080047000

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology

SALL4 gene was aberrantly expressed in many leukemia cell lines and primary leukemia cells of acute myeloid leukemia (AML). The aim of this study was to investigate the expression level of the gene and its clinical significance in patients with acute myeloid leukemia (AML). Quantitative real-time PCR (qrt-PCR) was performed to detect the expression level of SALL4 mRNA in the bone marrow or peripheral blood samples from 52 AML and 10 control samples. The results indicated that the expression level of SALL4 in AML (median: 2.0 RQ) was obviously higher than that in controls (media: 1 RQ) with p value: 0.001. There was no statistically significant difference between cases and control in SALL4 gene expression with the age, sex, WBC count, Hb concentration, platelet count, chromosomal abnormalities of AML patients, FAB and WHO classification (P > 0.05)

Issued also as CD

There are no comments on this title.

to post a comment.