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Evaluation of the effect of repeated intravitreal injections of Anti-VEGF on macular perfusion in diabetic patients using optical coherence tomography angiography / Ayman Gehad Elnahry ; Supervised Khaled Esmat Elrakhawy , Karim Adly Raafat , Ahmed Abdel Azim Abdelkader

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ayman Gehad Elnahry , 2019Description: 134 P. : charts , facsimiles ; 25cmOther title:
  • تقييم تأثير الحقن المتكرر داخل الجسم الزجاجى لمثبط عامل نمو بطانة الاوعية الدموية على سريان الدم فى الماقولة فى مرضى السكرى باستخدام الماسح الضوئى المقطعى المترابط [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Ophthalmology Summary: Purpose: To evaluate the effect of 3 intravitreal monthly bevacizumab injections for diabetic macular edema (DME) on the macular perfusion using spectral domain optical coherence tomography angiography (SD-OCTA). Methods: Treatment naïve patients with DME were prospectively recruited from Cairo University retina clinic. Included patients underwent full ophthalmological examination and SD-OCTA at baseline and after 3 intravitreal monthly bevacizumab injections. Both 6X6 and 3X3-mm macular scan protocols were used. Pre and post-treatment OCTA images were automatically aligned using a commercially available retina alignment software (i2k Align Retina software) then the fractal dimension (FD), vascular density (VD), and skeleton VD change following the injections were obtained at the full retinal thickness (Full) and the superficial (SCP) and deep (DCP) capillary plexuses after processing the aligned images using a semi-automated program. FD was calculated using the FracLac plugin of ImageJ. The foveal avascular zone (FAZ) area was measured manually using ImageJ and compared before and after treatment
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.24.Ph.D.2019.Ay.E (Browse shelf(Opens below)) Not for loan 01010110080196000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.24.Ph.D.2019.Ay.E (Browse shelf(Opens below)) 80196.CD Not for loan 01020110080196000

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Ophthalmology

Purpose: To evaluate the effect of 3 intravitreal monthly bevacizumab injections for diabetic macular edema (DME) on the macular perfusion using spectral domain optical coherence tomography angiography (SD-OCTA). Methods: Treatment naïve patients with DME were prospectively recruited from Cairo University retina clinic. Included patients underwent full ophthalmological examination and SD-OCTA at baseline and after 3 intravitreal monthly bevacizumab injections. Both 6X6 and 3X3-mm macular scan protocols were used. Pre and post-treatment OCTA images were automatically aligned using a commercially available retina alignment software (i2k Align Retina software) then the fractal dimension (FD), vascular density (VD), and skeleton VD change following the injections were obtained at the full retinal thickness (Full) and the superficial (SCP) and deep (DCP) capillary plexuses after processing the aligned images using a semi-automated program. FD was calculated using the FracLac plugin of ImageJ. The foveal avascular zone (FAZ) area was measured manually using ImageJ and compared before and after treatment

Issued also as CD

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