header
Image from OpenLibrary

C-MET(mesenchymal-epithelial transition factor) expression in colorectal adenomas and colorectal carcinoma : Histopathological and immunohistochemical study / Mai Soliman Mohammed Ahmed ; Supervised Solafa Amin Abdelaziz , Rasha Ahmed Khairy , Heba Abdelmonem Ibrahim

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mai Soliman Mohammed Ahmed , 2019Description: 145 P. : charts , facsimiles ; 25cmOther title:
  • تعبير مستقبل سى ميت فى أورام القولون الغدية الحميدة وسرطان القولون و المستقيم دراسة نسيجية مناعية [Added title page title]
Subject(s): Available additional physical forms:
  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology Summary: Background: Colorectal cancer (CRC) is currently the third most common cancer type worldwide and it is considered the most frequent gastrointestinal malignancy. Material & Methods: Twenty four cases of colorectal adenoma and 36 cases of primary colorectal carcinoma were studied to evaluate c-MET expression by immunohistochemistry and tumor budding on H&E slides. Results: A statistically significant difference of c-Met expression was present between normal colonic mucosa and carcinoma cases (P< 0.001). Statistically significant differences of c-MET expression were present among adenomas low grade dysplasia, adenomas high grade dysplasia and colorectal carcinomas (P=0.001). Expression of c-MET was positive in 45.8% of adenomas. A significant positive association was identified between c-MET high expression and degree of dysplasia (P<0.001). c- MET was highly expressed in 50.0% of primary colorectal carcinoma. Significant positive correlations were detected between c-MET expression and budding score. c-Met scores at the invasive front were significantly higher in tumors with high budding scores (P<0.001). There was no significant positive correlation between c-MET expression and TNM stage
Tags from this library: No tags from this library for this title. Log in to add tags.
Star ratings
    Average rating: 0.0 (0 votes)
Holdings
Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.27.M.Sc.2019.Ma.C (Browse shelf(Opens below)) Not for loan 01010110080562000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.27.M.Sc.2019.Ma.C (Browse shelf(Opens below)) 80562.CD Not for loan 01020110080562000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pathology

Background: Colorectal cancer (CRC) is currently the third most common cancer type worldwide and it is considered the most frequent gastrointestinal malignancy. Material & Methods: Twenty four cases of colorectal adenoma and 36 cases of primary colorectal carcinoma were studied to evaluate c-MET expression by immunohistochemistry and tumor budding on H&E slides. Results: A statistically significant difference of c-Met expression was present between normal colonic mucosa and carcinoma cases (P< 0.001). Statistically significant differences of c-MET expression were present among adenomas low grade dysplasia, adenomas high grade dysplasia and colorectal carcinomas (P=0.001). Expression of c-MET was positive in 45.8% of adenomas. A significant positive association was identified between c-MET high expression and degree of dysplasia (P<0.001). c- MET was highly expressed in 50.0% of primary colorectal carcinoma. Significant positive correlations were detected between c-MET expression and budding score. c-Met scores at the invasive front were significantly higher in tumors with high budding scores (P<0.001). There was no significant positive correlation between c-MET expression and TNM stage

Issued also as CD

There are no comments on this title.

to post a comment.