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Health related quality of life and its predictors among Egyptian children with beta-thalassemia / Marwa Ahmed Awad Abdelgalel ; Supervised Magy Samir Abdelwahab , Rasha Abdelraouf Abdelaziz , Marwa Abdelhady Abdelsamad

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Marwa Ahmed Awad Abdelgalel , 2019Description: 121 P. : charts , facsimiles ; 25cmOther title:
  • تقييم جودة الحياة المرتبطة بالصحة فى الاطفال المرضى بانيميا البحر المتوسط [Added title page title]
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  • Issued also as CD
Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Aim of work: to assess the health-related quality of life (HRQOL) of patients with b-thalassemia major and intermedia and its predictors.Patients and methods: This is a cross-sectional study conducted on 112 Thalassemia major and 88 Thalassemia intermedia patients. HRQOL was assessed by using Short Form-36 health survey questionnaire, version 2 (SF-36v2).Results: The mean ± SD age of the patients was 7.7 ± 3.8 years. After reviewing the patients' quality of life, it was observed that the mean score for physical function was 66.80, role limitations due to physical reasons 59.71, bodily pain 60.08, general health 39.90, fatigue or vitality 53.70, social function 60.09, role limitations due to psychological reasons (emotional) 46.59 and mental health 58.62. There was a negative correlation between frequency of blood transfusion domain and physical domain (r= -0.596, P<0.001) and also body pain domain (r=0.508, p<0.001). The ferritin level was a significant negative predictor for all domains except vitality. The gender of the patient was not found to be predictor for all domains.Conclusion: Thalassemia in children significantly affects HRQOL especially regarding general health, physical and mental aspects. Frequency of blood transfusion and ferritin level are negative predictors of QOL in these patients
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Item type Current library Home library Call number Copy number Status Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2019.Ma.H (Browse shelf(Opens below)) Not for loan 01010110080563000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2019.Ma.H (Browse shelf(Opens below)) 80563.CD Not for loan 01020110080563000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Aim of work: to assess the health-related quality of life (HRQOL) of patients with b-thalassemia major and intermedia and its predictors.Patients and methods: This is a cross-sectional study conducted on 112 Thalassemia major and 88 Thalassemia intermedia patients. HRQOL was assessed by using Short Form-36 health survey questionnaire, version 2 (SF-36v2).Results: The mean ± SD age of the patients was 7.7 ± 3.8 years. After reviewing the patients' quality of life, it was observed that the mean score for physical function was 66.80, role limitations due to physical reasons 59.71, bodily pain 60.08, general health 39.90, fatigue or vitality 53.70, social function 60.09, role limitations due to psychological reasons (emotional) 46.59 and mental health 58.62. There was a negative correlation between frequency of blood transfusion domain and physical domain (r= -0.596, P<0.001) and also body pain domain (r=0.508, p<0.001). The ferritin level was a significant negative predictor for all domains except vitality. The gender of the patient was not found to be predictor for all domains.Conclusion: Thalassemia in children significantly affects HRQOL especially regarding general health, physical and mental aspects. Frequency of blood transfusion and ferritin level are negative predictors of QOL in these patients

Issued also as CD

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