Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background: Inherited thrombophilia is the blood tendency to form thrombosis in children, whether arterial or venous and it may increase risk of recurrence and complication. Thromboembolism in children is multifactorial and more than one risk factor is mostly detected. Aim of this work is to describe patients with inherited thrombophilia, detect the prevalence of the genetic mutations in patients presented with thrombosis secondary to inherited thrombophilia in Cairo University Pediatric Hospital, identify the characteristics and clinical presentation of inherited thrombophilia in our Cohort of patients e.g. site of thrombosis, presenting symptoms, complications and recurrence and identify the most common interventions in our cases and management plan adopted in these children. Methods: This study is observational Cohort study conducted on 52 patients. The included patients had an inherited thrombophilia presented with thromboembolic manifestations. Medical records were reviewed for history of the disease and detecting the interventions that is mostly used

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