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The effect of vitamin D deficiency on myalgia in patients on ststins / Ashgan Wagdi Mohamed Abouhashim ; Supervised Yasser Mohamed Baghdady , Mohamed Hassanin Mohamed , Mohamed Shehata Abdalla

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Ashgan Wagdi Mohamed Abouhashim , 2019Description: 94 P. : charts , facsimile ; 25cmOther title:
  • تأثير نقص فيتامين د على ألم العضلات في المرضى الذين يتناولون العقاقير المخفضه للكوليسترول [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Cardiology Summary: Background: There is a multitude of evidence supporting the benefit of statin use in cardiovascular disease; however, statin-induced myopathy is a major reason for statin discontinuation and non- adherence. Vitamin D deficiency has been independently associated with muscle weakness and severe myopathy, and may be a confounder for statin-induced myopathies. Objectives: To determine whether low serum vitamin D associated with the occurrence of myalgia in statin treated patients. Patients and Methods: This cross-sectional study enrolled 60 statin-treated patients to assess vitamin D status. These patients were divided into two groups: 30 patients are taking statins and have myalgia and30patients are those taking statins yet not complaining of myalgia. Results: We studied 60 statin-treated patients, which consisted of 30 patients with myalgia at study entry and 30 asymptomatic patients. All 60 patients had controlled blood pressure, normal thyroid-stimulating hormone, thyroxin, creatinine, calcium, liver enzymes and normal CK level. The 30 symptomatic and 30 asymptomatic statin-taking patients did not differ (P >0.005) at study entry by age, BMI, types of statins, type 2 diabetes mellitus, weight, height, lipid profiles and HTN duration.The mean of duration of Statin intake (months) was lower in the 30 patients with myalgia than in the 30 asymptomatic patients (4.63 ± 1.71 VS 25.63 ± 13.04, P value < 0.001)
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.04.M.Sc.2019.As.E (Browse shelf(Opens below)) Not for loan 01010110080653000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.04.M.Sc.2019.As.E (Browse shelf(Opens below)) 80653.CD Not for loan 01020110080653000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Cardiology

Background: There is a multitude of evidence supporting the benefit of statin use in cardiovascular disease; however, statin-induced myopathy is a major reason for statin discontinuation and non- adherence. Vitamin D deficiency has been independently associated with muscle weakness and severe myopathy, and may be a confounder for statin-induced myopathies. Objectives: To determine whether low serum vitamin D associated with the occurrence of myalgia in statin treated patients. Patients and Methods: This cross-sectional study enrolled 60 statin-treated patients to assess vitamin D status. These patients were divided into two groups: 30 patients are taking statins and have myalgia and30patients are those taking statins yet not complaining of myalgia. Results: We studied 60 statin-treated patients, which consisted of 30 patients with myalgia at study entry and 30 asymptomatic patients. All 60 patients had controlled blood pressure, normal thyroid-stimulating hormone, thyroxin, creatinine, calcium, liver enzymes and normal CK level. The 30 symptomatic and 30 asymptomatic statin-taking patients did not differ (P >0.005) at study entry by age, BMI, types of statins, type 2 diabetes mellitus, weight, height, lipid profiles and HTN duration.The mean of duration of Statin intake (months) was lower in the 30 patients with myalgia than in the 30 asymptomatic patients (4.63 ± 1.71 VS 25.63 ± 13.04, P value < 0.001)

Issued also as CD

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