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CD163 versus CD68 immunohistochemistry in predicting outcome in classical hodgkin lymphoma in Egyptian patients / Mohamed Abdelmohsen Zaki Mostafa ; Supervised Nahed Abdelwahab , Osman Mansour , Reham Ahmed Rashed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohamed Abdelmohsen Zaki Mostafa , 2019Description: 233 P. : charts , facsimiles ; 25cmOther title:
  • الدراسة الكيمائية المناعية للانسجة ل 163 سي دى مقابل68 سي دى فى التنبؤ بتطور المرض فى سرطان هودجكين الكلاسيكى بالغدد الليمفاوية فى المرضى المصريين [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology Summary: Background: Hodgkin's Lymphoma is a malignant tumor of the lymphatic system, first recorded by Thomas Hodgkin in 1832. Tumor associated macrophages have been implicated in the pathogenesis of Classical Hodgkin Lymphoma and have been suggested to have a negative impact on outcome. CD 163 and CD 68 markers of the monocyte/macrophage lineage have been used to evaluate tumor associated macrophages. Aim of the study: The aim of this study is to determine the expression and the prognostic impact of CD 163 and CD 68 in the initial bone marrow biopsy specimens of our subjects by immunohistochemistry and to correlate their expression with other clinical and laboratory prognostic factors. Subjects and Methods: This study was conducted on fifty one patients with de novo Classical Hodgkin Lymphoma, presenting to the Clinical Pathology Department at the National Cancer Institute, Cairo university. CD 163 and CD 68 were detected in the initial bone marrow biopsy specimens from our subjects by immunohistochemistry
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.03.Ph.D.2019.Mo.C (Browse shelf(Opens below)) Not for loan 01010110080954000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.03.Ph.D.2019.Mo.C (Browse shelf(Opens below)) 80954.CD Not for loan 01020110080954000

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Clinical Pathology

Background: Hodgkin's Lymphoma is a malignant tumor of the lymphatic system, first recorded by Thomas Hodgkin in 1832. Tumor associated macrophages have been implicated in the pathogenesis of Classical Hodgkin Lymphoma and have been suggested to have a negative impact on outcome. CD 163 and CD 68 markers of the monocyte/macrophage lineage have been used to evaluate tumor associated macrophages. Aim of the study: The aim of this study is to determine the expression and the prognostic impact of CD 163 and CD 68 in the initial bone marrow biopsy specimens of our subjects by immunohistochemistry and to correlate their expression with other clinical and laboratory prognostic factors. Subjects and Methods: This study was conducted on fifty one patients with de novo Classical Hodgkin Lymphoma, presenting to the Clinical Pathology Department at the National Cancer Institute, Cairo university. CD 163 and CD 68 were detected in the initial bone marrow biopsy specimens from our subjects by immunohistochemistry

Issued also as CD

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