Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology

The present study was conducted to detect the prevalence of oral mucosal lesions within tobacco users, recruiting 840 subjects. The participants have been selected from the pool of the clinics of Oral Medicine and Periodontology Department and the Diagnostic center, Faculty of Dentistry -Cairo University. For each eligible participant, a full history was obtained according to a questionnaire (appendix) followed by thorough clinical examination. The Inclusion criteria were to include males and females in all age groups to detect the lesions among all the cohort, all patients were smokers and the study was done on individuals who agreed to sign the informed consent at the begging of the study. The exclusion criteria precluded individuals suffering from any systemic disease, individuals on medications and non-Egyptians to remove any potential confounders. The prevalence of lesions among recruited subjects was studied and it was 72.98%. Smoker melanosis seemed to be the most frequently reported lesion with a prevalence of 60%; followed by increased tongue coating which reached 40.8%. leukoedema was 29%, smoker{u2019}s palate 16%, candidiasis and black hairy tongue represented around 10.60 and 9.40 %, respectively. Lesions which were reported in less than 10% of the patients were smoker keratosis, leukoplakia and lichen planus. Malignant lesions (mostly OSCC) hit approximately 1 % of the smokers population. Other lesions include; aphthous ulcer, traumatic ulcer, frictional keratosis, morsicatio buccarum, recurrent herpetic lesions (intra-oral / labialis), Fordyce{u2019}s granules, fibroma, pyogenic granuloma, lichenoid reaction, chemical burn and physiologic pigmentation were present in 12.62% of the study population. Age was positively correlated with lesions prevalence with correlation coefficient (R2=0.38). While gender correlation with lesions was difficult due to small number of female subjects (n=12). The occurrence of multiple lesions was very common where more than 53 % of the recruited subjects suffered from more than one lesion

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