Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Oral and Maxillofacial Surgery

Several grafting materials have been used in the sinus floor augmentation procedures including autogenous bone(AB), Xenograft (Bio-Oss), inorganic bovine bone (ABB), platelet rich fibrin (PRF) , plasma rich fibrin (PRF), hydroxy appatite (HA), calcium sulfate and pegen P15 used AB as a comparator and the other six materials as interventions. Up to now a subject of controversy in maxillofacial surgery and dentistry is what is the most appropriate graft material for sinus floor augmentation. Purpose: The aim of the study is to provide a body of evidence-based data regarding grafting materials in sinus floor elevation concerning the quality of bone which measured by Histomorphometric analysis and the quantity of bone which measured by Cone Beam Computed-Tomography (CBCT), through a metaanalysis of the available literature. Materials and Methods: The literature searches were performed using PubMed search.The search covers only English, human and RCT literatures. For analyzing the quality and quantity of bone. After search strategy on PubMed we found 336 articles then after applying the inclusion and exclusion criteria the remaining RCT articles which met the criteria are 2 studies, which measures the bone quality only by Histomorphometric and no included RCT paper using CBCT. Results: In the remaining 2 articles the comparison occur between 2 materials which are autogenous bone and Bio-Oss using Histomorphometric analysis on 48 patients, which gives result in the first study AB=37.7 ± 31.3%, Bio-Oss=41.7 ± 26.6% and in the second study AB=42.74 ± 2.10%, Bio-Oss=24.90 ± 5.76%. Conclusion: The bone quality formed by Bio-Oss is less than autogenous bone by 17.1% so that the autogenous bone remains the gold standard grafting material

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