Evaluation of the diagnostic value of leptin and IGFBP{u2010}3 as markers in early detection of HCV related Hepatocellular Carcinoma / Ghadeer Abdelsalam Ali Elsafty ; Supervised Ismail Abdelshafy Abdelhamid , Abdelwahab Elghareeb , Abdelrahman Nabawi Zekri

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Ghadeer Abdelsalam Ali Elsafty

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TextLanguage: English Publication details: Cairo : Ghadeer Abdelsalam Ali Elsafty , 2019Description: 88 P. : charts ; 25cmOther title:

(كدلالات للكشف المبكر عن سرطان الكبد الأولى الناتج عن الالتهاب الكبدى الفيروسى (سى IGFBP- تقييم القيمة التشخيصية للبتين و 3 [Portion of title]

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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Science - Departement of Biotechnology Summary: This study was done to attempt assessing the possibility of using one of the biomarkers involved in Hepatocellular carcinoma (HCC) development, for early detection of HCC, these biomarkers include Leptin and IGFBP-3. In this study we measure the levels of these biomarkers in serum and plasma samples of liver cirrhosis (LC), chronic hepatitis C (CHC),HCC as well as healthy controls using ELISA technique. Our data supported the clinical significance of Leptin and IGFBP-3 in early detection of HCC. Thus, using the studied serological markers in combination with AFP may offer more efficient diagnosis over AFP alone in the early detection of HCCy

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Item type	Current library	Home library	Call number	Copy number	Status	Date due	Barcode
Thesis	قاعة الرسائل الجامعية - الدور الاول	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.12.25.M.Sc.2019.Gh.E (Browse shelf(Opens below))		Not for loan		01010110081187000
CD - Rom	مخـــزن الرســائل الجـــامعية - البدروم	المكتبة المركزبة الجديدة - جامعة القاهرة	Cai01.12.25.M.Sc.2019.Gh.E (Browse shelf(Opens below))	81187.CD	Not for loan		01020110081187000

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Thesis (M.Sc.) - Cairo University - Faculty of Science - Departement of Biotechnology

This study was done to attempt assessing the possibility of using one of the biomarkers involved in Hepatocellular carcinoma (HCC) development, for early detection of HCC, these biomarkers include Leptin and IGFBP-3. In this study we measure the levels of these biomarkers in serum and plasma samples of liver cirrhosis (LC), chronic hepatitis C (CHC),HCC as well as healthy controls using ELISA technique. Our data supported the clinical significance of Leptin and IGFBP-3 in early detection of HCC. Thus, using the studied serological markers in combination with AFP may offer more efficient diagnosis over AFP alone in the early detection of HCCy

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