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Role of recombinant activated factor VII (rFVII) in decreasing hysterectomy rate at primary post-partum hemorrhage / Mai Ramadan Elsaid ; Supervised Hatem Ibrahim Abedlmoety , Ahmed Hamdi Mohamed

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mai Ramadan Elsaid , 2020Description: 103 P. : charts , facsimiles ; 25cmOther title:
  • دور العامل المنشط والمؤتلف السابع المعدل وراثياً فى خفض معدل استئصال الرحم فى حالات النزيف ما بعد الولادة الأولى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics Summary: Objectives: The aim of the study is to evaluate efficacy of (rFVIIa, Novo Seven) in managing cases of primary post-partum hemorrhage (PPH) unresponsive to conventional methods in reducing the need to undergo hysterectomy. Methods:This study included 50 women in child bearing period that underwent normal vaginal delivery or cesarean section complicated by PPH participants were divided into two groups, each composed of 25 patients. Patients were distributed in each group according to whether Recombinant factor VIIa (rFVIIa) was included in the management ofPost-partum hemorrhage.The first group was composed of 25 patients (study group) who took rFVIIa.The second group was composed of 25 patients (control group) who did not receive rFVIIa. Results:Our results showed that group I (rFVIIa group) had a lower incidence of Hysterectomy and mortality but with no statistical significant difference according to (P-value > 0.05) as compared to group II. As regards to hysterectomy it was 6 (24%) in the group Iand 9 (36%) in the group II.The Maternal mortality was 8 patients in both groups it was 3 in group I and 5 in group II. Conclusion: rFVIIa is a beneficial therapeutic option that could reduce blood loss and contribute to reduction of maternal morbidities and mortalities in post-partum hemorrhage and in our study hysterectomy and mortality rate in the group which received rFVIIa was lower than the group who didn{u2019}t receive rFVIIa with no significant statistical difference between both groups
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.15.M.Sc.2020.Ma.R (Browse shelf(Opens below)) Not for loan 01010110081336000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.15.M.Sc.2020.Ma.R (Browse shelf(Opens below)) 81336.CD Not for loan 01020110081336000
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Cai01.11.15.M.Sc.2020.Ma.I The impact of cervical traction (Amr Maneuver) with passive management of third stage of labor in prevention of post partum hemorrhage, compared to active management : Randomized Control Study / Cai01.11.15.M.Sc.2020.Ma.I The impact of cervical traction (Amr Maneuver) with passive management of third stage of labor in prevention of post partum hemorrhage, compared to active management : Randomized Control Study / Cai01.11.15.M.Sc.2020.Ma.R Role of recombinant activated factor VII (rFVII) in decreasing hysterectomy rate at primary post-partum hemorrhage / Cai01.11.15.M.Sc.2020.Ma.R Role of recombinant activated factor VII (rFVII) in decreasing hysterectomy rate at primary post-partum hemorrhage / Cai01.11.15.M.Sc.2020.Mo.A The Association between body mass [ndex and intra-abdominal adhesions in women undergoing repeat caesarean sections / Cai01.11.15.M.Sc.2020.Mo.A The Association between body mass [ndex and intra-abdominal adhesions in women undergoing repeat caesarean sections / Cai01.11.15.M.Sc.2020.Mo.C Comparative study between vaginal misoprostol alone ــ a and the combination of vaginal misoprostol with isosorbide mononitrate in induction of labor in primiparas with premature rupture of membranes and low bishop /

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Gynecology and Obstetrics

Objectives: The aim of the study is to evaluate efficacy of (rFVIIa, Novo Seven) in managing cases of primary post-partum hemorrhage (PPH) unresponsive to conventional methods in reducing the need to undergo hysterectomy. Methods:This study included 50 women in child bearing period that underwent normal vaginal delivery or cesarean section complicated by PPH participants were divided into two groups, each composed of 25 patients. Patients were distributed in each group according to whether Recombinant factor VIIa (rFVIIa) was included in the management ofPost-partum hemorrhage.The first group was composed of 25 patients (study group) who took rFVIIa.The second group was composed of 25 patients (control group) who did not receive rFVIIa. Results:Our results showed that group I (rFVIIa group) had a lower incidence of Hysterectomy and mortality but with no statistical significant difference according to (P-value > 0.05) as compared to group II. As regards to hysterectomy it was 6 (24%) in the group Iand 9 (36%) in the group II.The Maternal mortality was 8 patients in both groups it was 3 in group I and 5 in group II. Conclusion: rFVIIa is a beneficial therapeutic option that could reduce blood loss and contribute to reduction of maternal morbidities and mortalities in post-partum hemorrhage and in our study hysterectomy and mortality rate in the group which received rFVIIa was lower than the group who didn{u2019}t receive rFVIIa with no significant statistical difference between both groups

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