Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Anesthesiology and Pain Relief

Breast cancer is the most common cancer in women. It represents about (38.8%) of all types of cancer affecting female in Egypt. Postoperative pain is one of the greatest patient concerns following any surgery. Patients undergoing breast surgery require a multimodal postoperative pain treatment regimen that provides high quality analgesia with minimal side effects.Until now, the routine practice in oncologic breast surgeries is that they are typically performed under general anesthesia (GA) with intra-operative and post-operative use of parenteral opioids. However, this technique cannot provide adequate postoperative pain control and routine use of parenteral opioids aggravate postoperative sedation, nausea, emesis, impaired oxygenation and depressed ventilation.Many studies have been carried out trying to find a solution for these dilemma thus different analgesic modalities as local infiltration of the surgical field, systemic analgesia, neuro-axial blocks, and nerve blocks¹⁵{u⁰⁰B⁰}

Issued also as CD