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Electrochemical and analytical studies for determination of some anti-depressant drugs / Neveen Saied Ibrahim ; Supertvised Amany Mohamed Fekry , Gehad Genidy Mohamed , Fekria Mosaad Abouattia

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Neveen Saied Ibrahim , 2020Description: 178 P. : charts , facsimiles ; 25cmOther title:
  • دارسات كهروكيميائية و تحميمية لتقدير بعض الأدوية المضادة للأكتئاب [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Analytical Chemistry Summary: This work has been carried out to determine vilazodone HCl (VILAHC), agomelatine (AGO) and duloxetine HCl (DULHC) as anti-depressant drugs in pure, pharmaceutical preparations and human urine using new electrochemical and HPLC procedures. Fabrication of different electrochemical sensors based on cellulose/nano titanium oxide/nano palladium chloride modified carbon paste electrode (C/T/Pd/MCPE), multiwalled carbon nanotubes/cellulose/tween modified carbon paste electrode (MWCNTs/C/T/MCPE) and sephadex/zinc oxide nanoparticles modified carbon paste electrode (S/ZnO/MCPE), for determination of VILHC, AGO and DULHC in presence of dopamine, respectively were used and exhibited low detection limits, high reproducibility, enhanced sensitivity, selectivity and unique stability. Also high performance liquid chromatographic method for the simultaneous determination of the selected antidepressant drugs and vitamin B12 (cyanocoblamine) was studied
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.08.Ph.D.2020.Ne.E (Browse shelf(Opens below)) Not for loan 01010110081455000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.12.08.Ph.D.2020.Ne.E (Browse shelf(Opens below)) 81455.CD Not for loan 01020110081455000

Thesis (Ph.D.) - Cairo University - Faculty of Science - Department of Analytical Chemistry

This work has been carried out to determine vilazodone HCl (VILAHC), agomelatine (AGO) and duloxetine HCl (DULHC) as anti-depressant drugs in pure, pharmaceutical preparations and human urine using new electrochemical and HPLC procedures. Fabrication of different electrochemical sensors based on cellulose/nano titanium oxide/nano palladium chloride modified carbon paste electrode (C/T/Pd/MCPE), multiwalled carbon nanotubes/cellulose/tween modified carbon paste electrode (MWCNTs/C/T/MCPE) and sephadex/zinc oxide nanoparticles modified carbon paste electrode (S/ZnO/MCPE), for determination of VILHC, AGO and DULHC in presence of dopamine, respectively were used and exhibited low detection limits, high reproducibility, enhanced sensitivity, selectivity and unique stability. Also high performance liquid chromatographic method for the simultaneous determination of the selected antidepressant drugs and vitamin B12 (cyanocoblamine) was studied

Issued also as CD

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