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Granisteron versus ondansetron for prophylaxis against post-spinal anesthesia shivering : A randomized controlledstudy / Noha Sameh Fahmy Hassen Darwish ; Supervised Nashwa Nabil Mohamed Talaat , Amr Raafat Refaat Mohammed , Ayman Amin Mohamed Ali Abougabal

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Noha Sameh Fahmy Hassen Darwish , 2020Description: 47 P. : charts , facsimiles ; 25cmOther title:
  • دراسة اكلنيكنية لمقارنة تأثير عقارى الجرانيسترون و الأندانسترون للحد من حدوث ارتعاش للجسم أثناء التخدير النصفى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Anaesthesia Summary: Background: Perioperative shivering is a common problem during anaesthesia. Apart from physical warming many pharmacological and non-pharmacological prevention and treatment modalities are present.Ondansetron has been used for preventing shivering during anaesthesia in several studies. Granisetronhas been recently evaluated for its perioperative anti shivering effect. Patients & Methods: 180 patients, undergoing elective surgeries under spinal anaesthesia with 15 mg of hyperbaric 0.5% bupivacaine plus 25 æg fentanyl was used for spinal anaesthesia. Before intrathecal injection, the patients were randomly divided into 2 equal groups, each group included 90 patients who received IV ondansetron 8 mg or granisetron 1mg. Vital signs , shivering and side effects i.e. hypotension, nausea and vomiting, were recorded. Results: Number of patients who developed shivering after spinal anesthesia was 23 patients (25%) in ondansetron group, 11 patients (12.5%) in granisetron group. Also, there was no significant difference between two groups (p= 0.288). Conclusion: Prophylactic intravenous injection of Granisetron (1mg) and ondansetron (8mg) before spinal anesthesia were effective in reducing the incidence of post spinal shivering, however, Granisteron was more effective than ondansetron
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.01.M.Sc.2020.No.G (Browse shelf(Opens below)) Not for loan 01010110082191000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.01.M.Sc.2020.No.G (Browse shelf(Opens below)) 82191.CD Not for loan 01020110082191000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Anaesthesia

Background: Perioperative shivering is a common problem during anaesthesia. Apart from physical warming many pharmacological and non-pharmacological prevention and treatment modalities are present.Ondansetron has been used for preventing shivering during anaesthesia in several studies. Granisetronhas been recently evaluated for its perioperative anti shivering effect. Patients & Methods: 180 patients, undergoing elective surgeries under spinal anaesthesia with 15 mg of hyperbaric 0.5% bupivacaine plus 25 æg fentanyl was used for spinal anaesthesia. Before intrathecal injection, the patients were randomly divided into 2 equal groups, each group included 90 patients who received IV ondansetron 8 mg or granisetron 1mg. Vital signs , shivering and side effects i.e. hypotension, nausea and vomiting, were recorded. Results: Number of patients who developed shivering after spinal anesthesia was 23 patients (25%) in ondansetron group, 11 patients (12.5%) in granisetron group. Also, there was no significant difference between two groups (p= 0.288). Conclusion: Prophylactic intravenous injection of Granisetron (1mg) and ondansetron (8mg) before spinal anesthesia were effective in reducing the incidence of post spinal shivering, however, Granisteron was more effective than ondansetron

Issued also as CD

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