Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology

Aim: The aim of the study is to compare the autogenous whole tooth graft (ATG) versus the autogenous demineralized dentin graft (ADDG) for their effect in alveolar ridge preservation (ARP) procedures concerning volumetric changes assessed by 3D cone beam computed tomography (CBCT) and histological analysis from selected sites. Methodology: A total of 12 sites with non-restorable teeth were randomly assigned into both study groups, 6 sites each. Atraumatic extraction was carried out, the extracted teeth were cleaned and ground then it was prepared into either ATG without demineralization or ADDG with demineralization in 0.6N HCl for 30 minutes. Graft material was then inserted in the extraction socket and covered by collagen membrane and suture. Baseline CBCT was taken on the day of the surgery and the final scan was taken after 6 months to assess bone height and width changes. In four sites were implants were placed, core biopsies were obtained from intervention and control sites for histological analysis. Results: After six months, all sites healed uneventfully. The reduction in horizontal bone width was 0.76±0.31mm for the ATG group and 0.90±0.40 mm for the ADDG group. The reduction in bone height was 0.53±0.21 mm buccally and 0.47±0.17 mm lingually for the ATG group while for the ADDG, the reduction corresponded to 0.68±0.30 mm buccally and 0.56±0.21 mm lingually. No statistically significant difference between both groups presented. Histologically, both graft types showed new bone formation. The ADDG showed direct contact with bone forming a dentin-bone union. The percentage of formed bone was higher in the ADDG with a value of 51.9% in comparison to the value of 35.2% for the ATG

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