Intraoperative motor evoked potential monitoring of facial nerve in patients undergoing cerebellopontine angle tumour resection using partial versus no neuromuscular block / Muhammad Magdy Gaber Elsaid ; Supervised Nasser Ahmed Fadel , Hisham Abdelwahab Aboeldahab , Amani Mahmoud Nawito

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Anaesthesia

Intraoperative neurophysiological monitoring has been established as one of the paths by which modern neurosurgery can improve surgical results while minimizing morbidity. Preservation of facial nerve (FN) function is a well-recognized goal of tumour excision at the cerebellopontine angle (CPA). So, it is necessary to compare the operating condition of two different levels of muscle relaxation on facial nerve monitoring We performed a comparative study on 40 Patients aged from 18-60 years old, scheduled for Cerebellopontine angle surgery. The number is 40 patients (20 per group) to compensate for possible dropoutsThis study recommended that intravenous infusion of muscle relaxant had shortened the duration of anesthesia and recovery time without significant effect on facial nerve monitoring end to start MEP amplitude ratio. Also, they decreased the doses of propofol needed for deep anesthesia.Regarding the comparison between the two study groups, it was founded that there was no significant difference between the effect of the muscle relaxant regarding hemodynamic stability, other drug doses as fentanyl, ephedrine or atropine and the duration of surgery

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