Comparative study between the liver imaging reporting and data system (LI-RADS) version 2017 and the conventional criteria-free approach in suspected hepatocellular carcinoma / Kholoud Morad Mohamed ; Supervised Amal Refaat Sayed Mohamed , Mohamed Samy Saied , Ahmed Abdellatif Mohamed

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology (in Radiation , Radiotherapy)

HCC is a global health problem, with the burden of disease expected to increase in the coming years and liver cirrhosis represents a major risk factor for the development of HCC. Imaging plays a pivotal role in the detection, diagnosis, staging, and management of HCC without the need for biopsy confirmation. Imaging results can be used to guide management, determine prognosis, and assess treatment response. However, to date there has been little to no standardization with regards to imaging technique, terminology and interpretation, report structure and content, and data collection. LIRADS is a diagnostic system developed by the ACR to standardize terminology, interpretation, and reporting for imaging examinations of the liver in patients at high risk for HCC .LIRADS should not be used to interpret CT or MRI in non{u2013} high-risk individuals. LIRADS is a comprehensive system that describes and categorizes the full spectrum of lesions and pseudolesions from benign to malignant encountered in patients at risk for HCC. It provides a diagnostic algorithm that guides radiologists through the process of assigning a category to observations that reflect the degree of suspicion for HCC. The five categories established by this system follow the diagnostic thought process and allow imaging observations to be categorized according to the risk of HCC

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