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Iv drug abusers infective Endocarditis; fate and Outcome after six months / Heba Elhadi Hamoda Essayeh ; Supervised Hossam Ibrahim Kandil , Marwa Sayed Meshaal , Reham Mohamed Darweesh

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Heba Elhadi Hamoda Essayeh , 2020Description: 126 P . : charts , facsmilies ; 25cmOther title:
  • مص{u٠٦أأ}ر ونت{u٠٦أأ}جه التهاب شغاف القلب المعدى بعد سته أشهر لمتعاطى المخدرات عن طر{u٠٦أأ}ق الحقن الور{u٠٦أأ}دى [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Cardiology Summary: To study fate and outcome of IE in IVDU patients who were admitted and managed by the IE working group in Kasr Al Ainy and to compare them to non IVDU-IE patients. Methods: This study included 102 patients diagnosed as intravenous drug use infective endocarditis during the period from February 2005 till the end of January 2020. Results: -One hundred and two patients diagnosed IVDU endocarditis with mean age of the studied patients was 31.01± 7.04 years. Tricuspid valve was the most affected in 76 (74.5%) of the cases. Staph-aureus was the most common pathogen in 64(62.7%) of cases. -Major complications during hospitalization were pulmonary embolism in 49(48.0%) of patients (was found to be statistically significant predictor for mortality with p value < 0.001), sepsis in 23(22.5%) of patients ( statistically significant predictor for mortality with p value 0.026), congestive heart failure was found in 21(20.6%) of patients (congestive heart failure was a significant predictor for surgery with p value 0.045), renal impairment was found in 38(37.3%) of patients [5(13%) of them complicated by renal failure (renal failure was strong predictor for surgery with p value 0.001)]. Splenic infarction in 5(4.9%). Cerebral stroke in 11(10.8%) of patients and Cerebral hemorrhage in 1%.Surgical intervention was done in 36.3% of cases. -In hospital mortality was (31.4%). -The other group included 102 patients diagnosed as non IVDU-IE and by comparing the two groups, we found in IVDU-IE male gender was predominant in 94% and average age was 31 years old, while in non IVDU-IE there was not a significant difference between males and females, 56% males VS 43% females and average age of patients was 32 years old. In non IVDU- IE patients, the most common complications were heart failure by 44%, followed by kidney impairment by 29.4%, then pulmonary embolism by 21.5%, sepsis by 16.6%, followed by cerebral embolism, arterial occlusion, splenic infarction, cerebral hemorrhage, and lastly, mycotic aneurysm with 14.7%, 13.7%,6.8%, 2.9%,1%, respectively
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Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.04.M.Sc.2020.He.I (Browse shelf(Opens below)) Not for loan 01010110082960000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.04.M.Sc.2020.He.I (Browse shelf(Opens below)) 82960.CD Not for loan 01020110082960000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Cardiology

To study fate and outcome of IE in IVDU patients who were admitted and managed by the IE working group in Kasr Al Ainy and to compare them to non IVDU-IE patients. Methods: This study included 102 patients diagnosed as intravenous drug use infective endocarditis during the period from February 2005 till the end of January 2020. Results: -One hundred and two patients diagnosed IVDU endocarditis with mean age of the studied patients was 31.01± 7.04 years. Tricuspid valve was the most affected in 76 (74.5%) of the cases. Staph-aureus was the most common pathogen in 64(62.7%) of cases. -Major complications during hospitalization were pulmonary embolism in 49(48.0%) of patients (was found to be statistically significant predictor for mortality with p value < 0.001), sepsis in 23(22.5%) of patients ( statistically significant predictor for mortality with p value 0.026), congestive heart failure was found in 21(20.6%) of patients (congestive heart failure was a significant predictor for surgery with p value 0.045), renal impairment was found in 38(37.3%) of patients [5(13%) of them complicated by renal failure (renal failure was strong predictor for surgery with p value 0.001)]. Splenic infarction in 5(4.9%). Cerebral stroke in 11(10.8%) of patients and Cerebral hemorrhage in 1%.Surgical intervention was done in 36.3% of cases. -In hospital mortality was (31.4%). -The other group included 102 patients diagnosed as non IVDU-IE and by comparing the two groups, we found in IVDU-IE male gender was predominant in 94% and average age was 31 years old, while in non IVDU-IE there was not a significant difference between males and females, 56% males VS 43% females and average age of patients was 32 years old. In non IVDU- IE patients, the most common complications were heart failure by 44%, followed by kidney impairment by 29.4%, then pulmonary embolism by 21.5%, sepsis by 16.6%, followed by cerebral embolism, arterial occlusion, splenic infarction, cerebral hemorrhage, and lastly, mycotic aneurysm with 14.7%, 13.7%,6.8%, 2.9%,1%, respectively

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