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The prognostic value of tumor-infiltrating lymphocytes in metastatic triple-negative breast cancer / Asmaa Ali Elshewy ; Supervised Ayman Abdelsamea Gaber , Rasha Mohamed Haggag , Iman Gouda Farahat

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Asmaa Ali Elshewy , 2021Description: 122 P. : charts , facsimiles ; 25cmOther title:
  • القيمة التكهنيه للخلايا الليمفاويه المتسلله للورم فى سرطان الثدى ثلاثى السلبيه المنتشر [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology (Medical) Summary: This study included 63 female metastatic triple negative breast cancer patients with mean age 48 years, Thirty two patients were premenopausal and 31 were postmenopausal. Most of our patients were from Great Cairo 48. Family history was positive in only 8 patients.The majority of cases (61) were presented with mass only. Most of our cases had Infiltrating Duct Carcinoma (IDC) 60 patients, Invasive lobular carcinoma in one case, Invasive Tubular carcinoma in one patient, Mucinous carcinoma in a patient. The median size of breast mass was five. N-stage of patients were as following: N0 (9.5%), N1 in (22.2%), N2 in (33.3%) and N3 in (31.7%) of patients. Pathological grades of tumor cells were II in 42 of cases and III in 21 of cases.The commonest sites of metastasis in our patients were lung in 40 (63.5%), bone 21 (33.3%), liver 18 (28.6%) and brain 9 (14.3%). Some patients presented by more than one site of metastasis. Surgical procedures were done for 50 patients, majority of them 44 did Modified Radical Mastectomy (MRM) and 6 patients did Breast Conserving Surgery (BCS).Regarding chemotherapy in our study 24 patients received neoadjuvant chemotherapy. Some of them complete all their chemotherapy before operations, others divided before and postoperative. Forty two patients received adjuvant chemotherapy. Fourteen patients were metastatic from start. All our patients which received neoadjuvant and adjuvant chemotherapy became metastatic later on
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.04.M.Sc.2021.As.P (Browse shelf(Opens below)) Not for loan 01010110083215000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.04.M.Sc.2021.As.P (Browse shelf(Opens below)) 83215.CD Not for loan 01020110083215000

Thesis (M.Sc.) - Cairo University - National Cancer Institute - Department of Oncology (Medical)

This study included 63 female metastatic triple negative breast cancer patients with mean age 48 years, Thirty two patients were premenopausal and 31 were postmenopausal. Most of our patients were from Great Cairo 48. Family history was positive in only 8 patients.The majority of cases (61) were presented with mass only. Most of our cases had Infiltrating Duct Carcinoma (IDC) 60 patients, Invasive lobular carcinoma in one case, Invasive Tubular carcinoma in one patient, Mucinous carcinoma in a patient. The median size of breast mass was five. N-stage of patients were as following: N0 (9.5%), N1 in (22.2%), N2 in (33.3%) and N3 in (31.7%) of patients. Pathological grades of tumor cells were II in 42 of cases and III in 21 of cases.The commonest sites of metastasis in our patients were lung in 40 (63.5%), bone 21 (33.3%), liver 18 (28.6%) and brain 9 (14.3%). Some patients presented by more than one site of metastasis. Surgical procedures were done for 50 patients, majority of them 44 did Modified Radical Mastectomy (MRM) and 6 patients did Breast Conserving Surgery (BCS).Regarding chemotherapy in our study 24 patients received neoadjuvant chemotherapy. Some of them complete all their chemotherapy before operations, others divided before and postoperative. Forty two patients received adjuvant chemotherapy. Fourteen patients were metastatic from start. All our patients which received neoadjuvant and adjuvant chemotherapy became metastatic later on

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