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Haploidentical hematopoietic stem cell transplantation in adult Egyptian patients with hematological malignancies / Mohamed Ali Maher ; Supervised Hossam Mohamed Kamel , Mohamed Abd Almooti Samra , Rafaat Mohamed AbdAlfataah

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Mohamed Ali Maher , 2020Description: 124 P. : charts , facsimiles ; 25cmOther title:
  • زرع الخلايا الجذعية من متبرع متوافق نصفيا في الأنسجة فى المرضى المصريين البالغين المصابين بالأورام الدموية الخبيثة [Added title page title]
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Dissertation note: Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology (Medical) Summary: Background:Despite advances in chemotherapy, allogeneic hematopoietic stem cell transplantation (HSCT) remains the best postremission therapy for patients with acute leukemia and unfavorable prognostic features at diagnosis, primary induction failure, or in second and third complete remission.Haploidentical stem cell transplantation (Haplo-HSCT) is a therapeutic option for patients without an HLA-matched donor. Haploidentical donors are generally available for most patients and stem cells can be rapidly obtained. Delays in transplantation while waiting for unrelated donor cells can be potentially problematic for patients with advanced disease at risk for progression; thus, the use of haploidentical donors, especially in this setting, can be life-saving.Objective: The aim of this study is assess toxicity, complications,Disease free survival overall survival, relapse, Transplant-related mortalities in patients diagnosed to have hematological malignancies who will undergo Haploidentical hemopoietic stem cell transplantation.Patients and methods:This is a retrospective study conducted by NCI BMT team in different centers. The study included 35 patients diagnosed to have hematological malignancies lacking HLA fully matched donor who will underwent Haploidentical hemopoietic stem cell transplantation
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.04.Ph.D.2020.Mo.H (Browse shelf(Opens below)) Not for loan 01010110083245000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.19.04.Ph.D.2020.Mo.H (Browse shelf(Opens below)) 83245.CD Not for loan 01020110083245000

Thesis (Ph.D.) - Cairo University - National Cancer Institute - Department of Oncology (Medical)

Background:Despite advances in chemotherapy, allogeneic hematopoietic stem cell transplantation (HSCT) remains the best postremission therapy for patients with acute leukemia and unfavorable prognostic features at diagnosis, primary induction failure, or in second and third complete remission.Haploidentical stem cell transplantation (Haplo-HSCT) is a therapeutic option for patients without an HLA-matched donor. Haploidentical donors are generally available for most patients and stem cells can be rapidly obtained. Delays in transplantation while waiting for unrelated donor cells can be potentially problematic for patients with advanced disease at risk for progression; thus, the use of haploidentical donors, especially in this setting, can be life-saving.Objective: The aim of this study is assess toxicity, complications,Disease free survival overall survival, relapse, Transplant-related mortalities in patients diagnosed to have hematological malignancies who will undergo Haploidentical hemopoietic stem cell transplantation.Patients and methods:This is a retrospective study conducted by NCI BMT team in different centers. The study included 35 patients diagnosed to have hematological malignancies lacking HLA fully matched donor who will underwent Haploidentical hemopoietic stem cell transplantation

Issued also as CD

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