Brief cognitive behavioral therapy for adherence and depression in patients with type 2 diabetes in an urban primary care facility : Randomized controlled trial / Nadine Mohamed Maged Ahmed Lotfy M Mansour ; Supervised Nargis Albert Labib , Mohamed Abdelfattah Khalil , Shereen Esmat Hussein

Thesis (Ph.D.) - Cairo University - Faculty of Medicine - Department of Community Medicine

Background: The relation between depression and diabetes is bidirectional and both can lead to morbidity and mortality. The majorities of studies that have investigated the burden of depression in T2D have been carried out in high income countries, but scarcely is done in the MENA. In Egypt, there are no published data on the effect of psychological interventions among patients with diabetes. Our aim was to assess the efficacy of cognitive therapy in patients with depression and uncontrolled diabetes. Methods/Design: This randomized controlled trial included 100 participants recruited from Al-agouza Family Medicine Center and allocated into treatment and control groups. The key inclusion criteria were uncontrolled type 2 diabetes (HbA1c >7.5%) and depression symptoms diagnosed by Beck{u2019}s Depression Index. The treatment group received four cognitive behavioral therapy sessions. Both groups were assessed at recruitment and three months after the intervention. Results: The ANCOVA results showed statistically significant improved depression symptoms (p = 0.010) to compare between the Cognative Behaivoral Therapy and control groups post-intervention. There was a statistically significant improvement in HbA1c (p = 0.042). However, there was an insignificant improvement in medication adherence between groups

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