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Role of lung ultrasound in predicting surfactant need in very low birth weight neonates / Hend Abdelkareem Sayed Mohamed Elnaggar ; Supervised Salma Zoheir Elhouchi , Hadeel Mohamed Seifeldin , Esraa Ahmed Mazzahy

By: Contributor(s): Material type: TextTextLanguage: English Publication details: Cairo : Hend Abdelkareem Sayed Mohamed Elnaggar , 2020Description: 82 P. : charts , facsimiles ; 25cmOther title:
  • دورالموجات فوق الصوتية على الرئة فى التنبؤ بالحاجة الى عقارالسرفاكتنت فى حديثى الولادة ذوى الوزن الناقص جدا [Added title page title]
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Dissertation note: Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics Summary: Background:Neonatal respiratory distress syndrome (RDS) is a leading cause of morbidity in preterm newborns (<34 weeks gestational age). Early surfactant administration within the first 2 to 3 hours of life reduces risk of death and/or bronchopulmonary dysplasia (BPD). Hence, the importance of diagnostic tools to guide the clinical decision of surfactant administration.Currently, radiographs are considered gold standard in understanding the etiology of respiratory distress (RD) in newborns. However excess exposure to radiation in a growing neonate in early part of life may have long term consequences. So there is a need for a non-invasive, bedside test, which is more baby friendly. lungultrasound(LUS) appears to be the ideal choice for such a screening or diagnostic tool in the assessment of RD in newborn. Methods: Prospective cohort study was carried on 80 Very low birth weight (VLBW), (<1.5 Kg) preterm (<34 weeks) newborns with RD admitted in two neonatal intensive care units (NICUs) affiliated to Kasr Alainy hospitalsFaculty of Medicine, Cairo University from October 2019 to February2020. All preterm neonates admitted were included and subjected to:Antenatal history taking including: history of maternal illness, maternal drug intake, antenatal corticosteroids, cause of premature delivery and mode of delivery, APGAR score assessment, Gestational age assessment using Ballard score, Anthropometric measurements, Chest X-ray (CXR) and LUS. Results: A cut-off value of (22.5) in the classic U/S score has a sensitivity of (87.5%) and a specificity of (67.9%). A cut-off value of (27.5) in the New US score has a sensitivity of (91.7%) and a specificity of (57.1%) in predicting need for surfactant for VLBW neonates
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Item type Current library Home library Call number Copy number Status Date due Barcode
Thesis Thesis قاعة الرسائل الجامعية - الدور الاول المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2020.He.R (Browse shelf(Opens below)) Not for loan 01010110084155000
CD - Rom CD - Rom مخـــزن الرســائل الجـــامعية - البدروم المكتبة المركزبة الجديدة - جامعة القاهرة Cai01.11.28.M.Sc.2020.He.R (Browse shelf(Opens below)) 84155.CD Not for loan 01020110084155000

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Pediatrics

Background:Neonatal respiratory distress syndrome (RDS) is a leading cause of morbidity in preterm newborns (<34 weeks gestational age). Early surfactant administration within the first 2 to 3 hours of life reduces risk of death and/or bronchopulmonary dysplasia (BPD). Hence, the importance of diagnostic tools to guide the clinical decision of surfactant administration.Currently, radiographs are considered gold standard in understanding the etiology of respiratory distress (RD) in newborns. However excess exposure to radiation in a growing neonate in early part of life may have long term consequences. So there is a need for a non-invasive, bedside test, which is more baby friendly. lungultrasound(LUS) appears to be the ideal choice for such a screening or diagnostic tool in the assessment of RD in newborn. Methods: Prospective cohort study was carried on 80 Very low birth weight (VLBW), (<1.5 Kg) preterm (<34 weeks) newborns with RD admitted in two neonatal intensive care units (NICUs) affiliated to Kasr Alainy hospitalsFaculty of Medicine, Cairo University from October 2019 to February2020. All preterm neonates admitted were included and subjected to:Antenatal history taking including: history of maternal illness, maternal drug intake, antenatal corticosteroids, cause of premature delivery and mode of delivery, APGAR score assessment, Gestational age assessment using Ballard score, Anthropometric measurements, Chest X-ray (CXR) and LUS. Results: A cut-off value of (22.5) in the classic U/S score has a sensitivity of (87.5%) and a specificity of (67.9%). A cut-off value of (27.5) in the New US score has a sensitivity of (91.7%) and a specificity of (57.1%) in predicting need for surfactant for VLBW neonates

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