Clinical and radiographic evaluation of advanced platelet rich fibrin in the preservation of alveolar ridge following atraumatic tooth extraction : A randomized clinical trial / Nahed Gamal Saleh Abdelaal ; Supervised Mona Salah Aldin Darhous , Marwa Amr Hassan Nawawy

Thesis (M.Sc.) - Cairo University - Faculty of Oral and Dental Medicine - Department of Periodontology

Aim: The study was aimed at determining the evaluation of hard and soft tissues at the extraction site when using advanced platelet rich fibrin compared to natural healing. Methodology: The present study was conducted on 30 subjects. Dental patients were recruited in a consecutive manner from the outpatient Diagnostic center, Faculty of Dentistry, Cairo University. Participants who fulfilled the inclusion criteria and provided informed consent were randomly assigned to either test or control group by means of simple randomization with a 1:1 allocation ratio. Consequently, the patients were allocated to receive either advanced platelet rich fibrin (APRF) (test group) or left for natural healing (control group).Alveolar ridge width, radiographic resorption mesial and distal to extraction site, gingival thickness and pain were measured at 2 months and 4 months follow up. All these parameters were subjected to a statistical analysis. Results: The buccolingual width result in the test group was decreased to 6.37±1.16mm while for the control groups, the values decreased to 5.95±0.53mm after 4 months with no statistical significance between the 2 groups. Both treatment protocols could not prevent bone resorption after 4 months. GT assessment showed a statistically significance increase only in APRF group after 2 and 4 months, but this gain was not statistically significant between the 2 groups.The mean mesial marginal bone level after 4 months in the test and control groups was 3.08 ± 1.43mm and 3.67 ± 1.37mm respectively with no statistical significance between the two groups.The mean distal marginal bone level after 4 months

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