Hepatic haemodynamics in non-alcoholic fatty liver disease : Acorrelative study between hepatic colour doppler ultrasonography and hepatic transient elastography / Ahmed Wagih Sadek Mohamed Ali ; Supervised Marwa Shaker Abdelfattah , Amr Abdelfattah Hassan , Mohamed Bassam Hashem

Thesis (M.Sc.) - Cairo University - Faculty of Medicine - Department of Radio-Diagnosis

Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the commonest causes of elevated liver enzymes encountered in the practice of hepatology and also a very important predisposing factor for chronic liver disease. Fatty infiltration of the liver parenchyma occurs with variable degrees in NAFLD; ranging from simple hepatic steatosis up to cirrhosis, and hepatocellular carcinoma. Our study is a cross-sectional analytical study performed on 40 NAFLD patients aimingto evaluate and compare the hepatic haemodynamic indices measured by ultrasonography and colour Doppler to the different quantified degrees of fibrosis and steatosis measured by transient elastography (FibroScan®), and to establish whether or not a significant statistical correlation exists between both modalities.Thestudy aims to emphasise the role of non-invasive imaging in the diagnosis of NAFLD as an alternative to the gold standard, liver biopsy. A higher incidence of fibrosis among male patients, a positive correlation between the splenic vein diameter and the degree of fibrosis, as well as, an inverse correlation between the portal vein resistivity index (RI) and the degree of steatosis were observed. Furthermore, an agreement was reached regarding the capabilities of both ultrasonography and transient elastography in the efficient diagnosis of liver steatosis

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